Keloids are fibroproliferative skin disorders that result from abnormal healing of irritated or injured skin. They contain inflammatory cells, newly formed blood vessels, fibroblasts in increased numbers, and excessive collagen deposits. 1 Their pathophysiology remains unknown but various mechanisms seem to be involved. There is now considerable evidence that keloidogenesis may be triggered by multiple systemic (e.g., adolescence, pregnancy, hypertension, and a variety of genetic and epigenetic factors) and local factors (e.g.,