Coronary artery ectasia (CAE) is a dilation of the coronary artery lumen. The term "ectasia" differs from "coronary aneurysm". The first one refers to diffuse dilation of a coronary artery, while the second designate a focal coronary dilation. In most of cases, it is associated with atherosclerotic disease. CAE predispose to acute coronary events because it disturbs coronary flow and increases blood viscosity. Conventionally, CAE was treated by oral anticoagulants and it has been considered as a valid treatment option. The usual treatment of acute coronary syndrome (ACS) including dual antiplatelet therapy (DAPT) is widely employed in CAE patients presenting with ACS.We report the case of a 71year-old man who suffered from angina chest pain revealing a myocardial infraction with inferior ST-elevation. Coronary angiography demonstrated diffused coronary artery ectasia with thrombotic occlusion in the distal segment of right coronary artery. It was managed with medical treatment including DAPT and oral anticoagulation.

Multisystem inflammatory syndrome in children (MIS-C) secondary to COVID-19 infection is associated with Multiorgan dysfunction, and prominent cardiovascular complications, particularly myocardial and coronary artery involvement, as well as thrombotic complications that make the prognosis more severe. The treatment of this entity is essentially based on the stabilization of the patient (management of shock…) and the intravenous immunoglobulin associated or not with corticosteroids as first line treatment. .We report the case of a 14year-old girl who suffered from influenza syndrome and cardiogenic shock revealing a Multisystem inflammatory syndrome including a cardiovascular manifestations and Disseminated Intravascular Coagulation (DIC) associated to COVID-19 infection. It was managed with medical treatment including inotropic drogus and immunomodulatory treatment with intravenous immunoglobulin (IVIG) associated to anti-inflammatory treatments including corticosteroids.

Original Research ArticleHigh blood pressure (hypertension) is a major cardiovascular risk factor and a public health problem in our country. Its implication in the occurrence of coronary disease is well established. However, there is a lack of recommendations that specify which patients should be screened for coronary artery disease. The aim of our study is to determine the predictive factors for the occurrence of coronary disease in the hypertensive population. This study took place over a 12-months period from November 2016 to November 2017, at the ERRAZI hospital in the CHU MOHAMMED VI cardiology department. The recruitment of patients was done from the volunteers of the patients of the service and the consultation. During this period, we identified 300 hypertensive patients, including 200 non-coronary patients and 100 coronary patients. For each patient, an interrogation, a clinical examination and an ECG were performed. Our data were studied first by a bivariate analysis and then the significant variables were finalized by a multivariate analysis. The results of our study showed a significant correlation between the occurrences of coronary disease in hypertensive patients: positive urine test strip, smoking, diabetes, male sex, hypertension duration and non-compliance therapeutic. Thus, we propose screening for coronary heart disease in mostly sedentary and / or smoking hypertensive patients and supplementing this work with other studies to establish a score to calculate the risk of occurrence of coronary heart disease in patients with high blood pressure.

FVII (factor VII) is vitamin K-dependently synthesized in the liver. Hepatopathies, vitamin K deficiency, or use of vitamin K antagonists are the causes of acquired deficiency. Other types of acquired FVII deficiencies are rare. However, based on literature the incidence might be underestimated. The clinical manifestation of acquired FVII deficiency varies greatly in severity; asymptomatic course as well as severe life-threatening bleeding diathesis and fatal bleedings have been described. In this case report, we discuss a unique presentation of a 79-year-old male who was found to have cardiac tamponade revealing a severe acquired factor VII deficiency. A discordance between a prolonged PT and a normal aPTT was found in the biology lab report. And the diagnosis was confirmed by obtaining a factor VII activity assay. His management involved correction of his factor VII deficiency with fresh frozen plasma and pericardiocentesis.

Introduction: The Churg-Strauss syndrome is a very rare systemic disease affecting people between 40-60 years old. It is recognized by the combination of blood eosinophilia, eosinophilic tissue infiltration, extravascular fibrinoid necrotizing (allergic) epithelioid and eosinophilic granuloma formation, and disseminated necrotizing vasculitis occurring in asthmatic patients. The diagnosis is based on well-defined criteria. The relation between blood eosinophilia and heart disease is well recognized with very heterogeneous damage. Mortality is associated with the cardiac manifestation of CSS in 50% of case. We conducted the current study to determine the prevalence and clinical impact of cardiac involvement in CSS patients. Methods: This was a retrospective and descriptive study about 11 patients followed in the Department of Internal Medicine of CHU Mohamed VI for Churg Strauss syndrome between the year 2017 and 2021. Results: The average age of our patients was 50 years. The sex ratio was 0, 57. The main cardiovascular risk factors were age, male sex, diabetes and hypertension, with a history of rhinitis in two patients and thyroidectomy in one patient. The diagnosis of CHURG-STRAUSS was based on the diagnostic criteria established by the American College of Rheumatology. The echocardiography was the basic examination to objectify the cardiac involvement with the following results: detection of a pericardial effusion in 2 cases, dilated cardiomyopathy in one patient and severe alteration of the ventricular function in one patient. The extracardiac injuries were divided into renal and neurological injuries. Corticosteroid therapy with Endoxan was the cornerstone of the treatment, with non-specific treatment depending on the clinical presentation.