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Neurofibromatosis type 1 (NF1) or Von Recklinghausen disease manifests as cutaneous café-au-lait spots and neurofibromas. It is one of the most common autosomal dominant genetic diseases. It is extremely variable in its individual manifestation. Cutaneous and neurologic symptoms are the most common manifestations but it can also affect other organs including eyes, bones and other areas. Lisch nodules are the most common ocular manifestations in NF-1. They are asymptomatic small pigmented iris tumors (iris hamartomas) which can help suggest the diagnosis of NF1 as they are characteristic of this disease and mostly occur in adult patients. We report the case of a 45-year old female patient followed for a neurofibromatosis type 1 retained on the presence of multiple cutaneous café-au-lait spots and neurofibromas. Ophthalmologic examination showed visual acuity of 10/10 P3 in both eyes. Biomicroscopic examination showed Lisch nodules of the iris in both eyes (A,B).

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Purpose: To evaluate the patient characteristics and to determine the factors affecting the development time and type of cataract occurring after pars plana vitrectomy (PPV) as well as the possible difficulties and/or complications encountered during and after this cataract surgery by phacoemulsification. Results: The mean patient age was 57 years. The etiology of the PPV (p=0.136), and the type of tamponade used (p=0.305) had no statistically significant effect on the type of cataract. The median interval between PPV and phacoemulsification was 11,2 months and there was no statistically significant difference in this interval in relation to age (inferior or superior than 50 years) (p=0.485), presence of diabetes (p=0.236), scleral buckling (p=0.72), etiology of vitrectomy (p=0.46) or the type of tomponade used (p=0.449). The main operational difficulty was the deep fluctuating anterior chamber (70%). Intraoperative complications included a capsulorhexis leak (5.7%), posterior capsular rupture (11.4%), zonular dialysis (2.85%) and dropped nucleus (2.85%). In postoperative, the most frequent complication was posterior capsule opacification, the other complications appear to be no more frequent and significant than on a non-vitrectomized eye. Conclusion:Cataract surgery after PPV is a challenge that requires special considerations from the cataract surgeon. To avoid intraoperative complications, the operator must know the different traps of this procedure and adapt his surgical technique.