━━ Background. Takotsubo cardiomyopathy (TCM) is characterized by Takotsubo-shaped apical akinesis and hyperkinesis in the basal segment of left ventricle, which was first described by Dote et al. in 1991. There have been many case reports on TCM associated with surgery, chemotherapy, and seizure; however, TCM associated with seizure due to brain metastasis from lung cancer is extremely rare. Case. A 72-year-old man underwent left upper lobectomy with lymph node dissection in February 20XX, (pT2aN0M0, stage IB, pleomorphic carcinoma). In September 20XX, he was referred to the emergency unit due to seizure and respiratory failure. Gadolinium-enhanced magnetic resonance imaging (MRI) of the brain showed a metastatic tumor accompanied by brain edema. Based on the Takotsubo-shaped left ventricle and low ejection fraction on echocardiography, we diagnosed him with TCM associated with brain metastasis of lung cancer. After treatment with anticonvulsant and anticoagulant drugs, his cardiac function soon improved, and he was discharged from the hospital on day 14 from emergent admission. Unfortunately, however, despite stereotactic body radiotherapy for the metastatic brain tumor, he died of cancer in October 20XX＋1. Conclusion. To our knowledge, this is an extremely rare case of TCM related to physical stress from seizure due to brain metastasis of lung cancer. An immediate diagnosis and treatment are essential, as TCM is sometimes misdiagnosed as ischemic heart disease.

A 75-year-old man visited his family doctor in 20XX-7 owing to an abnormal shadow on a chest radiograph revealed in a health check-up. Chest computed tomography (CT) showed a positive extrapleural sign for a 2.0-cm-diameter nodule in the left thoracic cavity. The nodule grew to a diameter of 2.9 cm in 20XX. Fluorodeoxyglucose positron emission tomography-CT showed weak accumulation. Thoracoscopic surgery was performed. The pedunculated tumor attached to the visceral pleura of the left lower lobe was removed by wedge resection. Histologically, the tumor had both a lowgrade area and a high-grade sarcomatous area with high mitotic counts. From the above histological features, the tumor was diagnosed as a dedifferentiated SFT that originated from the visceral pleura. Timely follow-ups are mandatory as dedifferentiated SFT has a higher rate of recurrence or metastasis than conventional SFT.

Background There have been few reports on surgically treated primary lung cancer accompanied by contralateral partial anomalous pulmonary venous connection (PAPVC). In such cases, repair of the PAPVC might be necessary to avoid postoperative right-heart failure due to the increased flow of the left-to-right shunt. Case presentation We herein report a case of lung adenocarcinoma treated by left-upper lobectomy with bronchoplasty and pulmonary arterial angioplasty after induction chemoradiation therapy followed by surgical correction of the PAPVC in the right-upper lobe. The patient is alive without recurrence of lung cancer or any symptoms of heart failure 17 months after pulmonary resection. Conclusion When considering performing major pulmonary resection for lung tumor, thoracic surgeons should pay close attention to the presence of a PAPVC not only on the ipsilateral side of the lung tumor, but also the contralateral side, although it is a rare phenomenon.

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