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Intraoperative electron beam radiotherapy (IOERT) is a technique in which a single-fraction high dose is intraoperatively delivered to subclinical tumour cells using an electron beam after breast-conserving surgery. In IOERT, an attenuation plate consisting of a pair of metal disks is commonly used to protect the normal tissues posterior to the breast. However, the dose in front of the plate is affected by backscatter, resulting in an unpredictable delivered dose to the tumour cells. In this study, an experimental attenuation plate, termed a shielding plate, was designed using Monte Carlo simulation, which significantly diminished the electron beam without introducing any backscatter radiation. The plate's performance was verified by measurements. It was made of two layers, a first layer (source side) of polymethyl methacrylate (PMMA) and a second layer of copper, which was selected from among other metals (aluminium, copper and lead) after testing for shielding capability and the range and magnitude of backscatter. The optimal thicknesses of the PMMA (0.71 cm) and copper (0.3 cm) layers were determined by changing their thicknesses during simulations. On the basis of these results, a shielding plate was prototyped and depth doses with and without the plate were measured by radiophotoluminescence glass dosimeters using a conventional stationary linear accelerator and a mobile linear accelerator dedicated for IOERT. The trial shielding plate functioned as intended, indicating its applicability in clinical practice.

We examined the dose distributions generated by Pinnacle3 (Philips Radiation Oncology Systems, Milpitas, CA) for intensity‐modulated radiotherapy (IMRT) plans using a cubic‐block‐piled compensator as the intensity modulator for 4‐MV and 10‐MV photon beams. The Pinnacle treatment planning system (TPS) uses an algorithm in which only the physical density of the absorber is required for calculating the characteristics of the modulator. The intensity modulator consists of cubic blocks (attenuator) of a tungsten alloy, plus cubic blocks of polyethylene resin foam that fill the spaces between the attenuator blocks and polymethyl methacrylate (PMMA) boards that act as the platform for the modulator. By measuring the transmission for various thicknesses of attenuator and by deriving values for the total physical density of the modulator, we determined the optimal effective density by comparing the curves fitted for the actual transmission data with the transmission calculated by the TPS. Using these effective densities, we examined the accuracy of Pinnacle3 for dose profiles of specific geometric patterns. The levels of consistency between the measurements and the calculations were within a tolerance of 3% of the dose difference and had a 3‐mm distance to agreement for the ladder‐, stairstep‐, and pyramid‐shaped test patterns, except in the high dose gradient region. In this modulator assembly, leakage occurred from the slits between the cubic blocks. This leakage was about 1.6% at maximum, and its influence on dose distribution was not crucial. In the TPS, in which physical density was the only user‐controllable parameter, we used the effective density of the absorber deduced from the effective mass attenuation coefficient. We conclude that the intensity modulation compensator system, together with a piled cubic attenuator, is clinically applicable, with an acceptable tolerance level. For the intensity map of the IMRT plan, measurements in treatment fields met 3% and 3‐mm criteria, excluding some regions of high gradient, which had a discrepancy of less than 5% and 4 mm.PACS numbers: 87.53.Mr, 87.53.Tf

To investigate the effects of scattered radiation when a thin titanium plate (thickness, 0.05 cm) used for skull fixation in cerebral nerve surgery is irradiated by a 4-MV photon beam. We investigated the dose distribution of radiation inside a phantom that simulates a human head fitted with a thin titanium plate used for post-surgery skull fixation and compared the distribution data measured using detectors, obtained by Monte Carlo (MC) simulations, and calculated using a radiation treatment planning system (TPS). Simulations were shown to accurately represent measured values. The effects of scattered radiation produced by high-Z materials such as titanium are not sufficiently considered currently in TPS dose calculations. Our comparisons show that the dose distribution is affected by scattered radiation around a thin high-Z material. The depth dose is measured and calculated along the central beam axis inside a water phantom with thin titanium plates at various depths. The maximum relative differences between simulation and TPS results on the entrance and exit sides of the plate were 23.1% and – 12.7%, respectively. However, the depth doses do not change in regions deeper than the plate in water. Although titanium is a high-Z material, if the titanium plate used for skull fixation in cerebral nerve surgery is thin, there is a slight change in the dose distribution in regions away from the plate. In addition, we investigated the effects of variation of photon energies, sizes of radiation field and thickness of the plate. When the target to be irradiated is far from the thin titanium plate, the dose differs little from what it would be in the absence of a plate, though the dose escalation existed in front of the metal plate.