Background: This study aimed to clarify factors affecting changes in moderate to vigorous physical activity (MVPA) in patients 1 to 3 months after undergoing percutaneous coronary intervention (PCI). Methods: In this prospective cohort study, we enrolled patients aged <75 years who underwent PCI. MVPA was objectively measured using an accelerometer at 1 and 3 months after hospital discharge. Factors associated with increased MVPA (≥150 min/wk at 3 mo) were analyzed in participants with MVPA < 150 minutes per week at 1 month. Univariate and multivariate logistic regression analyses were performed to explore variables potentially associated with increasing MVPA, using MVPA ≥ 150 minutes per week at 3 months as the dependent variable. Factors associated with decreased MVPA (<150 min/wk at 3 mo) were also analyzed in participants with MVPA ≥ 150 minutes per week at 1 month. Logistic regression analysis was performed to explore factors of declining MVPA, using MVPA < 150 minutes per week at 3 months as the dependent variable. Results: We analyzed 577 patients (median age 64 y, 13.5% female, and 20.6% acute coronary syndrome). Increased MVPA was significantly associated with participation in outpatient cardiac rehabilitation (odds ratio 3.67; 95% confidence interval, 1.22–11.0), left main trunk stenosis (13.0; 2.49–68.2), diabetes mellitus (0.42; 0.22–0.81), and hemoglobin (1.47, per 1 SD; 1.09–1.97). Decreased MVPA was significantly associated with depression (0.31; 0.14–0.74) and Self-Efficacy for Walking (0.92, per 1 point; 0.86–0.98). Conclusions: Identifying patient factors associated with changes in MVPA may provide insight into behavioral changes and help with individualized PA promotion.

Background Long-term prognosis after percutaneous coronary intervention (PCI), particularly non-target region stenosis, has not been well improved. Therefore, lifestyle modification should be considered along with medication to prevent the progression of coronary atherosclerosis. Particularly, the promotion of physical activity (PA) is recommended as a core intervention for secondary prevention because of its direct effects on coronary risk factors. However, the factors related to PA after PCI have not been fully investigated. Purpose To explore predictors of PA after discharge in patients underwent PCI. Methods We conducted a multicenter prospective cohort study. Participants were patients aged &lt;75 years who underwent PCI. The main outcome was PA {step counts (SC) and a time of moderate-to-vigorous physical activity (MVPA)} measured for 7 consecutive days using an accelerometer at 3-month post discharge. We collected demographic data, comorbidities, medical history, laboratory data, and medications from medical record. In addition, severity of chest pain at the onset, physician's explanation regarding long-term prognosis, exercise environments, social support, work, lifestyle except exercise, self-efficacy for walking, difficulty in daily activities and depression were evaluated using questionnaires at discharge and 1-month post-discharge. The study participants were divided into two groups based on the median SC and MVPA at 3-month, and clinical characteristics were compared between the groups using χ2test or Mann Whitney U test. Then, multiple logistic regression analysis adjusted for age, gender, and diagnosis {stable angina or acute coronary syndrome (ACS)} was conducted with 3-month PA as dependent variable. Independent variables were those with a p&lt;0.2 in the univariate analysis. In addition, the area under the curve (AUC) was calculated by receiver operating characteristic analysis to assess predictive accuracy of the regression model. Results We enrolled 313 patients [median age: 63 {inter-quartile range (IQR):56–67} years, women: 13.1%, ACS: 16.4%]. The median of SC and MVPA at 3-month were 6902 steps (IQR:5078–9095) and 16.2 min (IQR: 8.6–28.9), respectively. Predictors of SC at 3-month ≥the median were SC at 1-month (odds ratio 1.78, per 1000 steps/day; 95% confidence interval 1.51–2.09), hemoglobin (1.43, per 1g/dl; 1.10–1.86), body mass index (BMI) (0.87, per 1kg/m2; 0.82–0.99), use of β-blocker (0.49, 0.25–0.95), and self-efficacy for walking (1.06, per 1 point; 1.00–1.11). Predictors of MVPA ≥the median were MVPA at 1-month (5.66, per 10 minutes/day; 3.63–8.84), hemoglobin (1.57, per 1g/dl; 1.19–2.06), and BMI (0.85, per 1kg/m2; 0.76–0.94). The AUC of the regression model for SC and MVPA were 0.87 and 0.89, respectively. Conclusion PA after PCI could be predicted by modifiable factors with good predictive accuracy. The findings of this study suggest the possibility to develop tailored PA promotion program. Funding Acknowledgement Type of funding source: None

Objective：To investigate the physical functions of peripheral arterial disease(PAD) patients undergoing endovascular treatment(EVT) , and their association with physical activity before EVT.Methods：One hundred and one PAD patients underwent EVT. Physical functions were specified as grip strength, walking speed, and the weight ratio of knee extension isometric muscle strength(KEIS) . We divided the patients into 3 groups, based on the amount of physical activity per week： (a)low activity(0 kcal/week：n＝52) ,(b)moderate activity(0 kcal to less than 500 kcal/week：n＝22) , and(c)high activity(more than 500 kcal/week： n＝27) . Physical activity data were collected using an international standardized physical activity questionnaire. A multivariate regression analysis(cumulative logit model)was used to evaluate the association between physical activity(low activity, moderate activity, high activity)and KEIS ＜ 0.4 kgf/kg.Results：The averages of the physical functions were：grip strength(kg；Men 28.1, Women 16.6) , walking speed(m/ s；Men 1.10, Women 0.96) , KEIS(kgf/ kg；Men 0.42, Women 0.28) . The prevalence of KEIS ＜ 0.4 kgf/kg was 56.4％(n＝57) . KEIS ＜ 0.4 kgf/kg was not significantly different between low and moderate activity groups(Odds：0.99, p＝0.98) . However, KEIS ＜ 0.4 kgf/ kg was significantly different between low and high activity groups(Odds：5.02, p＝0.007) .Conclusion：Physical functions were lower in PAD patients undergoing EVT than in healthy adults of the same age, and KEIS was related to physical activity before EVT.