Background The potential benefit of mobile health (M-Health) in developing countries for improving the efficiency of health care service delivery, health care quality, and patient safety, as well as reducing cost, has been increasingly recognized and emphasized in the last few years. Objective Limited research has investigated the facilitators and barriers for the adoption of M-Health in developing countries to secure successful implementation of the technology. To fill this knowledge gap, we propose an integrative model that explains the patient's adoption behavior of M-Health in developing countries grounded on the unified theory of acceptance and use of technology, dual-factor model, and health belief model. Method We empirically tested and evaluated the model based on data collected using a survey method from 280 patients living in a developing country. Partial least squares (PLS-SEM) technique was used for data analysis. Results The results showed that performance expectancy, effort expectancy, social influence, perceived health threat, M-Health app quality, and life quality expectancy have a direct positive effect on patients’ intention to use M-Health. The results also showed that security and privacy risks have a direct negative effect on the patient's intention to use M-Health. However, resistance to change was found to have an indirect negative effect on patients’ intention to use M-Health through the performance expectancy. Conclusion The research contributes to the existing literature of health information systems and M-Health by better understanding how technological, social, and functional factors are associated with digital health applications and services use and success in the context of developing countries. With the widespread availability of mobile technologies and services and the growing demand for M-Health apps, this research can help guide the development of the next generation of M-Health apps with a focus on the needs of patients in developing countries. The research has several theoretical and practical implications for the health care industry, government, policy makers, and technology developers and designers.

Implementing a health information system (HIS) to enhance healthcare services and patients' experience has become a growing trend in developing countries. Yet little is known about acquainted users' attitudes on continuing the use of an HIS after adoption. Healthcare professionals (physicians and nurses in particular) are reluctant to use HISs because they perceive them as an interruption of their interaction with patients, thus negatively influencing their efficiency. In this study, we extend the technology acceptance model (TAM) by integrating habit as an exogenous variable that affects HISs' perceived ease of use (PEOU) and perceived usefulness (PU) to investigate experienced healthcare professionals' attitudes in continuing to use an HIS. The setting of this study is a developing country (Jordan) that implemented a nationwide HIS named Hakeem. The findings show that in the context of healthcare, attitude is the major determinant to continue using HISs. Findings also show that habit significantly increases healthcare professionals' perception of PU and PEOU, which improves their attitudes toward continuing to use HISs. These findings have implications for both research and practice.

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