Abstract: Objective: In the context of great attention given to fluoride containing restorative material and development of easily applied and reliable material for different clinical situations. This current study aimed to compare Bioactive resin-based composite (ACTIVA) to Resin modified glass ionomer (RMGI) in cervical restorations. Materials and methods:  Fuji II LC® capsules (conventional resin modified glass ionmer), or ACTIVA™ BioACTIVE-RESTORATIVE™ (enhanced resin-modified glass-ionmer) with using Etch-Rite™ and Prime&Bond universal (universal adhesive system) were applied randomly in thirty anterior teeth and six premolars with class V cavities; all materials were applied according to manufacturers’ instructions. Restorations were evaluated at baseline (one week), after six months, and after 12 months by two blinded assessors using modified USPHS criteria. Results:  The results in this study were ordinal data, so Mann-Whitney test was used to compare between tested materials. Freidman test was used to test the effect of time within tested materials. Kruskal Wallis test used to compare the interaction between variables for all tested parameters. The results were statistically significant when p≤0.05. There was no significant difference between interaction of both restorations and time in marginal discoloration (p=0.051), recurrent caries (p=1.00) and retention analysis (p=1.00), but there was a significant change in marginal adaptation (p=0.001), surface roughness (p=0.017), color change (p= 0.004) and surface luster (p=0.017) with 100 % survival rate in this study. Conclusions: Both conventional resin-modified glass ionmer and enhanced resin-modified glass ionomer are acceptable as intermediate restoration. Bioactive restorations proved to retain its esthetic characteristics over the conventional one. Bioactive restorations with an adhesive system can be used as long-term restoration in small-defined cavities, not in stress-bearing areas.   Clinical relevance: Within the limitations of this study, ACTIVA BIO-ACTIVE Restorative showed similar results to FUJI II LC in class V cavity restorations.