Highlights
Ahnak
−/−
mice were more resistant to the pulmonary metastasis of B16F10 cells.
Transcriptomic analyses revealed that PCSK9 was a candidate for lung metastasis.
The lung metastasis was suppressed in Scgb1a1-Cre/PCSK9
fl/fl
mice.
Ahnak-TGFβ-PCSK9 axis regulates pulmonary metastasis of B16F10 cells.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.