Problem statement. The high level of costs, energy and resource intensity in the field of construction leads to research aimed at improving the economic, social and environmental performance of construction processes from the standpoint of current trends in innovation in line with Industry 4.0. Especially relevant are studies adapted to the conditions of the national economy. The purpose of the article is to research of directions of development of technologies in the construction sphere, in particular technologies of 3D-printing, definition of ecological and economic advantages of transition to 3D-printing of construction objects in line with Industry 4.0. Results. The research of directions of development of 3D-printing technology is carried out, the types of 3D-printers are presented and characterized. Emphasis is placed on the need and benefits of assessment and certification of energy efficiency of buildings. The advantages of 3D printing are considered, which include the improvement of such parameters as environmental friendliness, speed and accessibility of construction. An assessment of the profitability and payback period of the construction business organization, which uses 3D-printing as the primary means of construction. It is established that the specific costs per 1m2 of 3D-construction in Ukraine will be about 4 thousand UAH, and the payback period of innovative construction business based on 3D-printing is less than a year. Scientific novelty and practical significance. For the first, an economic assessment of the construction business organization uses 3D printing as the primary means of construction, in the Ukrainian economy. The results of the study will be useful for business representatives in the field of construction, and can also be used in the training of specialists for the construction industry.