A female Cushing's syndrome patient had been suffering from extensive viral warts for months. She was diagnosed with flat warts, common warts and plantar warts. The plantar warts on her right foot were initially treated using local hyperthermia at 44°C for 30 min according to a defined protocol, followed by treatment targeting a common wart on her left thumb. In response to hyperthermia, the flat warts on her eyelid dissipated within 12 weeks, and when combined with a 1 week administration of imiquimod, the common warts and plantar warts completely disappeared within 8 weeks. There were no signs of recurrence and during this treatment her Cushing's syndrome was alleviated. This pioneer trial suggests that local hyperthermia may serve as an effective mean for treating multiple cutaneous warts under the conditions of a systemic immuno‐compromised disease.

The cover image is based on the Special Issue Article Local hyperthermia cleared multifarious viral warts in a patient with Cushing's syndrome by Ming‐Han Mu et al., https://doi.org/10.1111/dth.12815. Cover design credit: Rui‐Qun Qi. Photo credit: Min‐Han Mu and Yi‐Ning Wang. Institution credit: The First Hospital of China Medical University.