In the presence of dioxygen, an antimony trichloride enabled conjunctive sp3 C-H bond functionalization and carbochlorination of glycines was realized, providing a series of chlorinated quinolines in high yields. The...

No abstract

A tris(4-bromophenyl)aminium hexachloroantimonate-initiated oxidative Povarov-type reaction between glycines and methylenecyclopropanes was realized in the presence of dioxygen, in which the counterion, SbCl 6 − , served as a chlorine atom donor, enabling the synthesis of a series of chlorinated quinolines in high yields. The mechanistic study showed that the chlorination step might be related to antimony chloride via a radical chlorine atom transfer.

A TBN/O2 initiated oxidation of the relatively inert 3,4-C-H bonds of THIQs was accomplished, in which the existence of an α-phosphoric ester group is crucial to enable the dioxygen trapping...