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Controllable and directional bubble transport is usually the critical step in applications involving bubbles. However, current bubble transport strategies either are limited in controllability and transport distance or require the assistance of a specific external field. Here, we propose a strategy for bubble transport in an asymmetric hexagonal cage (ASHC), which works smoothly even under antibuoyancy conditions. The transport efficiency of bubbles can be greatly improved by adjusting the structural parameters of the cage. The control of the bubble depends only on the change of the bubble’s volume, so there is no strict restriction on the driving force, which can be pressure, photothermal, electrothermal, and even acoustic-thermal forces. Moreover, we demonstrate that long-distance transport and controllable merging of bubbles can be easily achieved by cascading multistage ASHC structures. This investigation offers a simple, low-cost, extensible, and versatile construction for bubble transport for fundamental research and practical applications.