Background As a rare benign lung tumour, pulmonary sclerosing pneumocytoma (PSP) is often misdiagnosed as atypical peripheral lung cancer (APLC) on routine imaging examinations. This study explored the value of enhanced CT combined with texture analysis to differentiate between PSP and APLC. Methods Forty-eight patients with PSP and fifty patients with APLC were retrospectively enrolled. The CT image features of the two groups of lesions were analysed, and MaZda software was used to evaluate the texture of CT venous phase thin-layer images. Independent sample t-test, Mann–Whitney U tests or χ2 tests were used to compare between groups. The intra-class correlation coefficient (ICC) was used to analyse the consistency of the selected texture parameters. Spearman correlation analysis was used to evaluate the differences in texture parameters between the two groups. Based on the statistically significant CT image features and CT texture parameters, the independent influencing factors between PSP and APLC were analysed by multivariate logistic regression. Extremely randomized trees (ERT) was used as the classifier to build models, and the models were evaluated by the five-fold cross-validation method. Results Logistic regression analysis based on CT image features showed that calcification and arterial phase CT values were independent factors for distinguishing PSP from APLC. The results of logistic regression analysis based on CT texture parameters showed that WavEnHL_s-1 and Perc.01% were independent influencing factors to distinguish the two. Compared with the single-factor model (models A and B), the classification accuracy of the model based on image features combined with texture parameters was 0.84 ± 0.04, the AUC was 0.84 ± 0.03, and the sensitivity and specificity were 0.82 ± 0.13 and 0.87 ± 0.12, respectively. Conclusion Enhanced CT combined with texture analysis showed good diagnostic value for distinguishing PSP and APLC, which may contribute to clinical decision-making and prognosis evaluation.

Abstract-Based on the "Opinions on the implementation of pilot Work of Modern Apprenticeship" issued by the Ministry of Education of China, this paper analyzes the effectiveness of curriculum reform under the "modern apprenticeship" education model for the curriculum of accounting major in higher vocational colleges. That is how to make vocational colleges, enterprises, government, and students achieve a four win situation. This paper first elaborates the necessity and meaning of studying the "modern apprenticeship" educational model. Then it briefly introduces the research situation of "modern apprenticeship" both at home and abroad and the influence of the "modern apprenticeship" educational model on higher vocational education. Besides, this paper analyzes the problems in the curriculum system of accounting major in higher vocational colleges under the current mode of cooperation between colleges and enterprises. Finally, the innovative advantages of the curriculum system optimization made by accounting major of higher vocational colleges by applying the "modern apprenticeship" education mode is presented and the outlook for development prospects of higher vocational colleges under this mode is put forward.