Filamentary keratitis (FK) is a chronic and recurrent disorder of the cornea. FK is reportedly associated with various kinds of ocular surface diseases or conditions. Until now, there have been lacks of studies based on quantitative sample analysis concerning FK incidence regularity and inducement characteristics at different ages. This was a retrospective study of 147 patients (162 eyes) with FK who had been continuously and completely recorded from August 2012 to August 2015 at the Second Affiliated Hospital of Zhejiang University in Hangzhou, east of China. Our results suggest that the causative factors of FK varied at different ages and the distribution of filaments on the corneal surface was also diverse with different inducements.By exploring the frequency and clinical features of FK, we believe that the findings from our research will be clinically significant and aid in the early prevention and treatment guidance of the disease.

Purpose: To investigate the corrective effect of combined use of orthokeratology and atropine eye drops on myopia of young children, as well as the factors involved. Methods: 84 young children with adolescent myopia who were admitted to Ningbo First Hospital from March 2019 to January 2021, were enrolled in this study. Forty (40) of the patients were treated with orthokeratology (control group, CG); while 44 patients were treated with a combination of orthokeratology and 0.01 % atropine (study group, EG). Clinical efficacy, pupil diameter, vision recovery, and incidence of adverse reactions were determined in both groups before and after treatment. Based on post-treatment clinical efficacy, patients in markedly effective and effective categories were regarded as improved status, while those whose treatments were ineffective were categorized in unimproved status. Logistic regression analysis was used to identify the influencing factors. Results: There was no significant difference in total treatment effectiveness between the two groups. However, post-treatment diameter of eye axis and axial growth of RG were lower in EG than in CG (p < 0.05). There were no marked differences in naked eye vision and incidence of adverse reactions between the two groups. Logistic regression analysis revealed that age and course of disease were the risk factors that significantly affected treatment effectiveness (p < 0.05). Conclusion: Combined treatment with orthokeratology and atropine eye drops relieves myopia in young children, and early treatment improves treatment effectiveness. However, further clinical trials are required prior to application in clinical practice.