The development of the skills to read and understand scientific literature is crucial to the future success of students. A literature review project was introduced into an organic chemistry laboratory course, in which undergraduate students were asked to acquire the skills of scientific literature searching, reading, and summarizing. The course project was improved during the COVID-19 pandemic, and a step-by-step study schedule in 7 weeks was carried out. The students wrote and handed in their reviews successfully through the training process. The literature review helped the undergraduate students to get a further comprehensive understanding of the relationship between organic chemistry and medical science.