† Modified based on the grading method set forth by the U.S. Preventive Services Task Force. ‡ http://www.cebm.net/oxford-centre-evidence-based-medicine-levels-evidence-march-2009/. § Modified based on the grading method of Sung et al. 9 RCT, randomized controlled trial.Journal of Digestive Diseases 2017; 18; 63-83 Chinese consensus on preventing CRC Statement 4: Long-term heavy alcohol consumption is a high-risk factor for CRC Evidence level: IIb Grade of recommendation: B Consensus level: 100% Alcohol consumption has a certain correlation with the risk of CRC. Huxley et al. 38 systemically analyzed the risk factors associated with CRC and reviewed the data from 103 cohort studies. The results showed that risk of CRC in groups with the highest alcohol consumption was 60% higher than that in the J-Y Fang et al.
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