INTRODUCTION: Dysphagia may result from a variety of different disease processes, including inflammation, infection, motility disorders, mechanical causes, or even functional. The etiology is less clear when a patient presents with multiple individual causes of dysphagia, each alone which may account for their symptoms. Our case report describes the coexistence of dysphagia due to several factors in a single patient, and a puzzling presentation warranting further evaluation to ultimately alleviate the underlying complaint. CASE DESCRIPTION/METHODS: We present a case of a 62-year-old female with a past medical history of hypertension that presented to her PCP with 6 months of weakness and limited oral intake. She endorsed issues swallowing and sensation of food stuck in her throat. Dysphagia to solids progressed to include liquids, and with nausea, vomiting, and 40 lbs unintended weight loss. The patient was admitted and failed bedside swallow study. Upper GI series and CT thorax showed hiatal and paraesophageal hernias. EGD revealed GE junction angulation from hernias, as well as esophagitis and gastritis. Manometry demonstrated weak swallows and sparse motility representative of a motility disorder. A gastric tube was placed for continued poor oral intake. She did not tolerate tube feeds, and gastric emptying study showed decreased emptying with marked GERD. EGD biopsies resulted and were consistent with eosinophilic esophagitis and H. pylori. She was prescribed triple therapy and started on PPI. She then had good symptom improvement and was discharged. At 6 week follow-up, the patient was able to tolerate oral intake and plans were initiated for gastric tube removal. DISCUSSION: Our patient exhibited numerous clinical findings that could account for her symptoms: esophageal herniations, eosinophilic esophagitis, H. pylori, an intrinsic motility disorder, and GERD. Though dysphagia has various etiologies, it is exceedingly rare for a single patient to display multiple simultaneous findings that might each individually explain their symptoms. Our case is unique in that the patient demonstrated sources from many different levels, yet given resolution with medication, likely originated from the primary eosinophilic esophagitis. Further investigation revealed the complexities of her case, and culminated in the eventual diagnosis, treatment, and symptomatic improvement. Our case also emphasizes the importance of thorough evaluation, as initial findings may be more complex than first realized.

INTRODUCTION: Percutaneous endoscopic gastrostomy (PEG) is commonly used to provide enteral nutrition in patients unable to maintain adequate nutrition orally. There is limited data on aneurysmal bleeding following PEG. When this occurs, it is typically severe and is a life-threatening complication leading to hemorrhagic shock. Prompt recognition and treatment are imperative to survival. Extensive literature review revealed five case reports of post-PEG pseudoaneurysm. We present a summary of reported cases and their respective management. CASE DESCRIPTION/METHODS: We present a case of a 50-year-old female, status post orthotopic liver transplant, who had a complicated post-op course and ICU stay. The patient developed a cerebral infarct in Pons region which led to dysphagia. Therefore underwent PEG tube placement by “pull” technique. Later on, the patient experienced recurrent episodes of PEG site bleeding. She underwent EGD which showed massive upper GI bleed from percutaneous endoscopic gastrostomy fistula tract. Hemostasis was initially achieved using bear claw but also required endoclips and surgical intervention in the end. CT imaging revealed a pseudoaneurysm at the PEG site within the rectus muscle, arising from the epigastric artery, measuring 19.8 mm × 17.8 mm. It was treated with thrombin injection. The resolution of aneurysmal bleed was confirmed on follow up imaging. DISCUSSION: We found 5 similar cases with patients 70 to 85 years old, who predominantly had a pull technique PEG tube placement. Imaging confirmed gastrostomy site pseudoaneurysm, involing left gastric or gastroepiploic artery, was a complication in all cases which were either treated by lipiodol injection, angiographic embolization and/or thrombin injection. Our patient had a pseudoaneurysm involving epigastric artery which is a novel presentation. Placement of PEG with transillumination carries a risk of rare complication if inserted in an upper triangle involving superior epigastric artery. Therefore an attempt must be made to keep PEG away from the superior epigastric triangle. Pull technique is used much more commonly and It is unlikely to be the cause of these aneurysmal complications however, data is limited and more review studies are needed. Also, more evidence is needed to compare outcomes of the transillumination method vs US/fluoroscopic guidance placement.

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