A novel mesoporous γ-Fe2O3-modified nanoflower-MnO2/attapulgite catalyst has been fabricated through a facile hydrothermal method and used for low temperature SCR of NOx with NH3.

The SID1 transmembrane family, member 2, namely, Sidt2, is a highly glycosylated multichannel lysosomal transmembrane protein, but its specific physiological function remains unknown. Lysosomal membrane proteins are very important for the executive functioning of lysosomes. As an important part of the lysosomal membrane, Sidt2 can maintain the normal morphology of lysosomes and help stabilize them from the acidic pH environment within. As a receptor/transporter, it binds and transports nucleic acids and mediates the uptake and degradation of RNA and DNA by the lysosome. During glucose metabolism, deletion of Sidt2 can cause an increase in fasting blood glucose and the impairment of grape tolerance, which is closely related to the secretion of insulin. During lipid metabolism, the loss of Sidt2 can cause hepatic steatosis and lipid metabolism disorders and can also play a role in signal regulation and transport. Here, we review the function of the lysosomal membrane protein Sidt2, and focus on its role in glucose and lipid metabolism, autophagy and nucleotide (DNA/RNA) transport.

A novel titanium dioxide–graphene–polyaniline (TiO2–RGO–PANI) hybrid was prepared by the one-pot method and used as a nonenzymatic electrochemical sensor for glucose detection. The composition and structural morphology of the as-prepared composites were determined by X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM). The characterization results showed that TiO2–RGO–PANI is mainly composed of Ti, O, C and N and their weight percentages are 67.68%, 21.57%, 10.70% and 0.05%, respectively, indicating that the TiO2–RGO–PANI composite catalyst has been successfully prepared and presents a poriferous coral structure. A series of electrochemical tests such as cyclic voltammetry tests declared that TiO2–RGO–PANI composite possessed a low limit of detection (LOD) (7.46[Formula: see text][Formula: see text]M), good repeatability, selectivity and stability. In the concentration range of 10–180[Formula: see text][Formula: see text]M, the hybrid presented linear diffusion, and the linear equation was [Formula: see text] (C/mM), the correlation coefficient [Formula: see text]. In addition, the comparison of the merits of this proposed electrode with some recent nonenzymatic glucose sensors indicates that this highly sensitive TiO2–RGO–PANI complex glucose sensor provides a simple, low-cost, nonenzymatic method for glucose detection, and has promising applications in clinical diagnostics and medical analysis.

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