The Bio-Oss group had favorable radiologic features (higher alveolar bone level and bone density with less premolar tipping) but showed slower OTM than the control group. The late OTM subgroup had favorable radiologic features and showed faster tooth movement than the early OTM in the β -TCP group.

Background: Guided Bone regeneration (GBR) has gained popularity in clinical dental practice. However, there is limited number of studies regarding the molecular and physical effects of bone regeneration materials (BRMs) on healing bone defects, which is essential for optimum clinical outcome.