We present a large, tunable neural conversational response generation model, DIALOGPT (dialogue generative pre-trained transformer). Trained on 147M conversation-like exchanges extracted from Reddit comment chains over a period spanning from 2005 through 2017, DialoGPT extends the Hugging Face PyTorch transformer to attain a performance close to human both in terms of automatic and human evaluation in single-turn dialogue settings. We show that conversational systems that leverage DialoGPT generate more relevant, contentful and context-consistent responses than strong baseline systems. The pre-trained model and training pipeline are publicly released to facilitate research into neural response generation and the development of more intelligent opendomain dialogue systems. * A collaboration between Microsoft Research and Microsoft Dynamics 365 AI Research.

Abstract. Image segmentation is a fundamental problem in biomedical image analysis. Recent advances in deep learning have achieved promising results on many biomedical image segmentation benchmarks. However, due to large variations in biomedical images (different modalities, image settings, objects, noise, etc), to utilize deep learning on a new application, it usually needs a new set of training data. This can incur a great deal of annotation effort and cost, because only biomedical experts can annotate effectively, and often there are too many instances in images (e.g., cells) to annotate. In this paper, we aim to address the following question: With limited effort (e.g., time) for annotation, what instances should be annotated in order to attain the best performance? We present a deep active learning framework that combines fully convolutional network (FCN) and active learning to significantly reduce annotation effort by making judicious suggestions on the most effective annotation areas. We utilize uncertainty and similarity information provided by FCN and formulate a generalized version of the maximum set cover problem to determine the most representative and uncertain areas for annotation. Extensive experiments using the 2015 MICCAI Gland Challenge dataset and a lymph node ultrasound image segmentation dataset show that, using annotation suggestions by our method, state-of-the-art segmentation performance can be achieved by using only 50% of training data.

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Many deep learning architectures have been proposed to model the compositionality in text sequences, requiring a substantial number of parameters and expensive computations. However, there has not been a rigorous evaluation regarding the added value of sophisticated compositional functions. In this paper, we conduct a point-by-point comparative study between Simple Word-Embeddingbased Models (SWEMs), consisting of parameter-free pooling operations, relative to word-embedding-based RNN/CNN models. Surprisingly, SWEMs exhibit comparable or even superior performance in the majority of cases considered. Based upon this understanding, we propose two additional pooling strategies over learned word embeddings: (i) a max-pooling operation for improved interpretability; and (ii) a hierarchical pooling operation, which preserves spatial (n-gram) information within text sequences. We present experiments on 17 datasets encompassing three tasks: (i) (long) document classification; (ii) text sequence matching; and (iii) short text tasks, including classification and tagging. The source code and datasets can be obtained from https:// github.com/dinghanshen/SWEM.