Feature detection and correct matching are the basis of the image stitching process. Whether the matching is correct and the number of matches directly affect the quality of the final stitching results. At present, almost all image stitching methods use SIFT+RANSAC pattern to extract and match feature points. However, it is difficult to obtain sufficient correct matching points in low-textured or repetitively-textured regions, resulting in insufficient matching points in the overlapping region, and this further leads to the warping model being estimated erroneously. In this paper, we propose a novel and flexible approach by increasing feature correspondences and optimizing hybrid terms. It can obtain sufficient correct feature correspondences in the overlapping region with low-textured or repetitively-textured areas to eliminate misalignment. When a weak texture and large parallax coexist in the overlapping region, the alignment and distortion often restrict each other and are difficult to balance. Accurate alignment is often accompanied by projection distortion and perspective distortion. Regarding this, we propose hybrid terms optimization warp, which combines global similarity transformations on the basis of initial global homography and estimates the optimal warping by adjusting various term parameters. By doing this, we can mitigate projection distortion and perspective distortion, while effectively balancing alignment and distortion. The experimental results demonstrate that the proposed method outperforms the state-of-the-art in accurate alignment on images with low-textured areas in the overlapping region, and the stitching results have less perspective and projection distortion.

Analyzing highly individual-specific genomic data to understand genetic interactions in cancer development is still challenging, with significant implications for the discovery of individual biomarkers as well as personalized medicine. With the rapid development of deep learning, graph neural networks (GNNs) have been employed to analyze a wide range of biomolecular networks. However, many neural networks are limited to black box models, which are only capable of making predictions, and they are often challenged to provide reliable biological and clinical insights. In this research, for sample-specific networks, a novel end-to-end hierarchical graph neural network with interpretable modules is proposed, which learns structural features at multiple scales and incorporates a soft mask layer in extracting subgraphs that contribute to classification. The perturbations caused by the input graphs' deductions are used to evaluate key gene clusters, and the samples are then grouped into classes to produce both sample- and stage-level explanations. Experiments on four gene expression datasets from The Cancer Genome Atlas (TCGA) show that the proposed model not only rivals the advanced GNN methods in cancer staging but also identifies key gene clusters that have a great impact on classification confidence, providing potential targets for personalized medicine.