Aquifer vulnerability maps can improve groundwater management for sustainable anthropogenic development. The latest update of karst aquifer vulnerability mapping is named: the Protection of Aquifers base on Protection, Rock type, Infiltration and KArstification (PaPRIKa). This multi-criteria assessment method is based on a weighting system whose criteria are selected according to the aquifer under study. In this study, the PaPRIKa method has been applied in the Fontaine de Vaucluse karst aquifer using the novel plugin for Quantum Geographic Information System (QGIS) software. The Fontaine de Vaucluse karst aquifer is the largest European karst hydrosystem with a catchment area that measures approximately 1162 km 2 . Four thematic maps were produced according to the criteria of protection, rock type, infiltration, and karst development. The plugin expedites the weighting system test and generates the final vulnerability map. At a large scale the vulnerability map is globally linked with primary geomorphological units and at the local scale is mostly affected by karst features that drive hydrodynamics. In conclusion, the novel QGIS plugin standardizes the application of the PaPRIKa method, saves time and prevents user omissions. The final vulnerability map provides useful contributions that are most relevant to groundwater managers and decision-makers. We highlight the sensibility of the vulnerability map to the weighting system and validation issues of the vulnerability map are raised.
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