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Context/Background: Earlier studies have shown a possible correlation between skin health and physical activity. Moreover, the COVID-19 pandemic has impacted physical activity levels due to many reasons. Aims/Objectives: This study aims to analyze the correlation between physical activity and dermatology quality of life during the COVID-19 pandemic. Methodology: A cross-sectional study was conducted in Surakarta, Central Java, Indonesia. This study used Dermatology Life Quality Index (DLQI) and International Physical Activity Questionnaire Short Form (IPAQ-SF) in Bahasa Indonesia to measure dermatology quality of life and physical activity. Results: A total of 207 adults participated in this study. Our study showed that females are at risk for developing a DLQI score >10 (PR: 1.91, 95% CI: 4.05-9.03). There is no significant relationship between physical activity measured in IPAQ-SF with skin-related quality of life measured by DLQI. Conclusions: A significant relationship was observed between the female sex and comorbidity with a skin condition that impairs life quality. However, this study found no significant relationship between physical activity measured in IPAQ-SF with skin-related quality of life measured in DLQI.

Preterm delivery is associated with higher mortality and morbidity of neonates, also increasestheir risk of having growth and development impairment.This study aimed toidentify the role ofgenital tract infection in preterm delivery. A retrospective study was conducted on medical records of mothers who had preterm delivery in a tertiary hospital in Surakarta, Indonesia during 2017. The data collected were mothers' age and their gestational age, the history of current pregnancy, the number of previous abortion(s), mothers' body temperature, the extent of abnormal vaginal discharge, and laboratory findings (white blood cell count, platelet count, red blood cell count, hemoglobin count, hematocrit level, urinalysis and microbiology results). The statistical differences amongst categorical and numerical data were analyzed using the Chi-Square test and the Mann-Whitney test. Based on the patient's history and the examination results, we suspected genital tract infections in22.52% (25/111)of subjects. All of them had abnormal vaginal discharge despite only one case had been confirmed as streptococcal infection. This study found that the majority of mothers with probable genital tract infection hadpreterm premature rupture of the membrane whilst preeclampsiawas more evident in those without genital tract infection. We conclude that genital tract infection during pregnancy is a significant contributor to the occurence of premature birth so that microbiological testing is needed to confirm the diagnosis. ABSTRAK Kelahiran preterm berkaitan dengan meningkatnya mortalitas dan morbiditas neonatus, serta meningkatkan risiko terjadinya kelainan tumbuh kembang. Penelitian ini bertujuan untuk mengidentifikasi peranan infeksi saluran genital terhadap kelahiranpreterm. Penelitian dilakukan secara retrospektif menggunakan data rekam medis dari ibu-ibu yang melahirkanpreterm di sebuah rumah sakit tersier di Surakarta, Indonesia pada tahun 2017. Data yang dikumpulkan adalah usia ibu dan usia kehamilan,riwayat kehamilan saat ini, jumlah abortus sebelumnya, suhu tubuh ibu hamil, adanya keputihan yang abnormal, dan hasil pemeriksaan laboratorium (hitung sel darah putih, hitung trombosit, hitung sel darah merah, hitung hemoglobin, kadar hematokrit, urinalisis, dan hasil pemeriksaan mikrobiologi).Perbedaan statistik yang ada padadata kategorikal dan numerik dianalisis menggunakan uji Chi-Square dan uji Mann-Whitney. Berdasarkan data hasil anamnesis dan pemeriksaan, 25 dari 111 subjek penelitian (22,52%) diduga menderita infeksi saluran genital. Pasien yang terduga infeksi tersebut seluruhnya mengalamikeputihan yang abnormal meskipun hanya satu kasus yang terdiagnosis infeksi streptokokus. Pada penelitian ini didapatkan ketuban pecah dini preterm pada mayoritas ibu hamil yang dicurigai menderita infeksi saluran genital sedangkan preeklampsia lebih banyak dijumpai pada kelompok ibu hamilyang tidak terinfeksi. Dapat disimpulkan bahwa infeksi saluran genital berperan penting dalam terjadinya kelahiran prematur sehingga pemeriksaan mikrobiologi...

Genital tract infection (GTI) remains a significant health concern. It is estimated that in 2016, there were 370 million people who suffer from chlamydia, gonorrhea, and trichomoniasis; and 708 million others suffer from genital herpes and condyloma acuminatum. It has been reported that in pregnant women, GTI is associated with preterm delivery. The mechanisms of GTI-associated preterm delivery need to be further understood to prevent neonatal mortality and morbidity that could be the risk factor for neonates’ growth and development disorders. This article aims to describe various types of GTI and the associated pathogenesis causing preterm birth. A literature search was conducted to retrieve recent articles published in English from online databases including Pubmed, ScienceDirect, and Google Scholar. This literature study found that GTI evokes inflammatory responses that trigger several mechanisms leading to preterm delivery. The inflammatory responses in GTI include the production of proinflammatory cytokines and robust activation of neutrophils. The key mechanisms that stimulate preterm delivery in GTI include the events of early uterine contraction, preterm premature rupture of membranes, and induction of cervical ripening; which are under normal circumstances in a full-term pregnancy, those mechanisms are regulated by progesterone and prostaglandin levels along with suppression of the inflammatory responses. In conclusion, this paper has described the underlying mechanisms of preterm delivery in pregnant women with ISG. However, such mechanisms remain unclear in candida and gonococcal infection; thus, prompting the need for further studies.

ABSTRAK Penyakit kusta masih menjadi masalah kesehatan di negara endemis, termasuk Indonesia. Di antara komplikasi penyakit kusta, ulkus plantar kronis meningkatkan morbiditas dan stigma terhadap kusta. Terapi konvensional untuk ulkus plantar pada pasien kusta tidak menyediakan faktor pertumbuhan yang cukup dan terkait dengan proses penyembuhan luka yang lama. Studi terdahulu melaporkan bahwa implementasi panduan atau konsep baru pada praktik klinis memerlukan waktu yang bervariasi, dari 12 bulan hingga 17 tahun. Oleh karena itu, kegiatan pengabdian masyarakat ini bertujuan untuk meningkatkan pengetahuan di antara mahasiswa Fakultas Kedokteran Universitas Muhammadiyah Surakarta mengenai situasi kusta di Indonesia dan prinsip tata laksana ulkus plantar kronis pada pasien kusta. Kegiatan pengabdian masyarakat ini dilakukan melalui acara bedah buku. Pengetahuan awal peserta dianalisis dengan pretest. Hasil pretest menunjukkan variabilitas pada tingkat pengethuan peserta pada beberapa aspek. Untuk aspek situasi terkini kusta, pengetahuan peserta cukup baik, dibuktikan dengan persentase jawaban benar pada pretest terkait aspek tersebut mencapai 66,7% dan 80,7%. Pengetahuan mengenai ulkus kusta di antara peserta masih kurang. Hal ini terlihat dari persentase jawaban benar yang hanya 43,9%. Pada awal acara, peserta yang memahami mengenai prinsip penatalaksanaan ulkus plantar hanya mencapai 36,8%. Selanjutnya pendekatan kualitatif oleh persepsi pemateri digunakan untuk menilai tingkat pengetahuan peserta selama dan setelah acara bedah buku.  Setelah dilakukan bedah buku, diamati adanya peningkatan pengetahuan peserta mengenai situasi kusta di Indonesia dan terutama mengenai prinsip tata laksana ulkus plantar kronis pada pasien kusta. ABSTRACT Leprosy remains major health problem in endemic countries, including Indonesia. Amongst the complication of leprosy is the chronic plantar ulcer which add to the disease morbidity and stigma. Standard treatment for chronic plantar in leprosy did not provide enough growth factor and was associated with prolonged healing process. Previous studies reported variety in implementing new guideline or new concept into clinical practice, from 12 months to 17 years. Thus, this community service aimed to increase awareness and understanding amongst medical student of Universitas Muhammadiyah Surakarta in regards to leprosy epidemiology in Indonesia and especially principal management of chronic plantar ulcers in leprosy. The community service activity was carried out by delivering a book review. Participants’ prior knowledge were assessed using pretest. Pretest results showed variability in participants' knowledge. For current situation of leprosy, the result was good with the score were ranging from 66.7% to 80.7%. However, there are lack of understanding on leprosy ulcer and the basis of plantar ulcer treatment in leprosy, as the pretest score showed 43.9% and 36.8%, respectively for each aspect. A qualitative approach was then used to assess participants’ comprehension during and after the book review. The results showed that the book review increased participants' understanding of leprosy situation in Indonesia and especially about principal management of chronic plantar ulcers in leprosy.