Renal pelvic cancer with a large vein tumor thrombus is very rare. We report a case of transitional cell carcinoma of the right renal pelvis with tumor thrombus in the inferior vena cava. Based on the radiological findings, the patient was diagnosed having renal cell carcinoma with tumor thrombus in the vena cava preoperatively. Radical nephrectomy with thrombectomy was performed. A literature review of 17 reported cases revealed that 13 cases (76.5%) were diagnosed as renal cancer preoperatively. Prognosis of transitional cell carcinoma with vena cava tumor thrombus is relatively poor compared to that of renal cell carcinoma with a large vein tumor thrombus.
A 53-year-old man was found to have a gallbladder tumor during a routine follow-up more than 10 years after nephrectomy for renal cell carcinoma in 1991. Computed tomography demonstrated a 2.5 × 2.5 cm pedunculated mass with strong contrast enhancement that was hypervascular on celiac angiography. Laparoscopic cholecystectomy was performed. The grossly resected surgical specimen contained two pedunculated polypoid tumors originating from muscular layer. The histopathology showed clear cell carcinomas that were predominantly below the mucosal layer. The cancer cells stained positive for glycogen and epithelial membrane antigen, but not for carcinoembryonic antigen, vimentin, or cytokeratin 7. The final pathologic diagnosis was gallbladder metastasis from renal cell carcinoma. Our case is only the 8th reported case of a solitary metastasis within the gallbladder from renal cell carcinoma.
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