The chondrocytes cultured on a poly-HEMA-coated dish and PLGA scaffolds showed chondrocyte-specific phenotypes and morphological appearance.

Objectives The aim of this study was to evaluate the pathognomic findings of magnetic resonance image(MRI) and determine the benefit of MRI in early diagnosis of invasive fungal sinusitis(IFS). Methods We retrospectively reviewed 15 cases of biopsy-proven IFS. The preoperative MRI was reviewed to identify the pathognomic findings and correlation between radio-graphic and surgical findings were investigated. Results The MRI findings included decreased signal intensity on T1-weighted images with no enhancement on contrast-enhanced images and markedly decreased signal intensity on T2-weighted images in all cases. In our series, the interval between the onset of symptom and timing of MRI was from 48 hours to 2 weeks. Radiographic findings were correlated with histopathologic findings in 13 of 15 patients. Conclusions We could find typical MRI findings in IFS. MRI should be considered early in patients at high risk for IFS.

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