Hydrogels consist of a cross-linked porous polymer network and water molecules occupying the interspace between the polymer chains. Therefore, hydrogels are soft and moisturized, with mechanical structures and physical properties similar to those of human tissue. Such hydrogels have a potential to turn the microscale gap between wearable devices and human skin into a tissue-like space. Here, we present material and device strategies to form a tissue-like, quasi-solid interface between wearable bioelectronics and human skin. The key material is an ultrathin type of functionalized hydrogel that shows unusual features of high mass-permeability and low impedance. The functionalized hydrogel acted as a liquid electrolyte on the skin and formed an extremely conformal and low-impedance interface for wearable electrochemical biosensors and electrical stimulators. Furthermore, its porous structure and ultrathin thickness facilitated the efficient transport of target molecules through the interface. Therefore, this functionalized hydrogel can maximize the performance of various wearable bioelectronics.
Wearable electronic devices are used to perform various electronic functions on the human skin, and their mechanical softness while maintaining high performances is critical. Therefore, there is a need to develop novel materials with outstanding softness and high electrical and ionic conductivity for wearable electronics. Here, we present an intrinsically stretchable and conductive nanocomposite based on alginate hydrogels and silver nanowires (AgNWs). The developed nanocomposite was applied to highly conductive soft electrodes that can be used in various wearable electronic devices. The nanocomposite electrode was prepared by cross-linking alginate molecules in the presence of AgNWs, exhibiting higher electrical, ionic conductivity, higher stretchability, and lower modulus than conventional conducting rubbers. By forming a bilayer structure with the nanocomposite and the ultrasoft hydrogel layer, the mechanical properties of the nanocomposite device could be matched to that of the human skin. We used the nanocomposite electrode for fabricating key device components of wearable electronics, such as a wearable antenna and a skin-mountable supercapacitor. Such demonstrations successfully proved the effectiveness of the proposed nanocomposite as a soft conducting material for wearable electronics.
In the era of the Fourth Industrial Revolution, artificial intelligence (AI) is a core technology, and AI-based applications are expanding in various fields. This research explored the influencing factors on end-user’s intentions and acceptance of AI-based technology in construction companies using the technology acceptance model (TAM) and technology–organisation–environment (TOE) framework. The analysis of end-users’ intentions for accepting AI-based technology was verified by applying the structure equation model. According to the research results, the technological factors along with external variables and an individual’s personality had a positive influence (+) on the perceived usefulness and the perceived ease of use of end-users of AI-based technology. Conversely, environmental factors such as suggestions from others appeared to be disruptive to users’ technology acceptance. In order to effectively utilise AI-based technology, organisational factors such as the support, culture, and participation of the company as a whole were indicated as important factors for AI-based technology implementation.
The low delivery efficiency of light‐responsive theranostic nanoparticles (NPs) to target tumor sites, particularly to brain tumors due to the blood–brain barrier, has been a critical issue in NP‐based cancer treatments. Furthermore, high‐energy photons that can effectively activate theranostic NPs are hardly delivered to the target region due to the strong scattering of such photons while penetrating surrounding tissues. Here, a localized delivery method of theranostic NPs and high‐energy photons to the target tumor using microneedles‐on‐bioelectronics is presented. Two types of microneedles and flexible bioelectronics are integrated and mounted on the edge of surgical forceps. Bioresorbable microneedles containing theranostic NPs deliver the NPs into target tumors (e.g., glioblastoma, pituitary adenoma). Magnetic resonance imaging can locate the NPs. Then, light‐guiding/spreading microneedles deliver high‐energy photons from bioelectronics to the NPs. The high‐energy photons activate the NPs to treat tumor tissues by photodynamic therapy and chemotherapy. The controlled thermal actuation by the bioelectronics accelerates the diffusion of chemo‐drugs. The proposed method is demonstrated with mouse tumor models in vivo.
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