BackgroundThe aim of this study is to analyze mortality in patients treated with bevacizumab for wet AMD.MethodsWe conducted a retrospective case-control study between patients who received intravitreal injections of bevacizumab as the sole treatment for exudative AMD between September 2008 and October 2014 (n = 5385) and age and gender matched controls (n = 10,756). All individuals included in the study were reviewed for sociodemographic data and comorbidities. Survival analysis was performed using adjusted Cox regression, using relevant adjusted variables.ResultsDuring follow-up (maximum: 73 months), 1063 (19.7%) individuals after bevacizumab died compared with 1298 (12.1%) in the control group (P < .001). After adjusted Cox survival regression, mortality differed significantly between the groups, Odds ratio = 1.69, (95% C.I. 1.54–1.84), P < .001.ConclusionsWe found an increased long-term mortality in individuals with wet AMD treated with bevacizumab compared to a same age and gender group without wet AMD.

Nurses should assess for patients' expectations and barriers that could impede pain relief and provide appropriate interventions.

Additional investigation should be conducted to identify the factors that influence sleep disturbances in patients with cancer at home and the relationship between sleep disturbance and numbness and tingling.

OBJECTIVES:The purpose of this study was first to determine internal consistency reliability of the Ono Decision Making Career and Workplace (ODMCW) questionnaire. Next, a comparison of the reasons for a professional career and workplace choices of occupational therapists (OTs) and speech and language pathologists (SLPs) was evaluated. PARTICIPANTS: Participants consisted of 174 women (89 [51%] OTs and 85 [49%] SLPs). INSTRUMENT:The ODMCW questionnaire contains 17 items each scored on a 5 point scale in 2 parts (Career Choice and Workplace). The ODMCW was distributed to participants of both professions. RESULTS: Analysis of the questionnaire revealed 4 factors that together explained 56.87% of the variance of Career Choice with moderate to good Cronbach's alpha coefficients ranging from 0.524-0.789. The findings for both career and workplace choice show differences between the two professional groups, where SLPs give more weight to the factor of employment terms and benefits (p < 0.01) as well as work conveniences (p < 0.001), while OTs give more weight to professional and academic stature (p < 0.05). CONCLUSIONS: These initial findings should lead to more studies within these professions and others, as well as in different cultural groups to further understand the reasons and motives for Career Choices.

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