The spread of epidemics has always threatened humanity. In the present circumstance of the Coronavirus pandemic, a mathematical model is considered. It is formulated via a compartmental dynamical system. Its equilibria are investigated for local stability. Global stability is established for the disease-free point. The allowed steady states are an unlikely symptomatic-infected-free point, which must still be considered endemic due to the presence of asymptomatic individuals; and the disease-free and the full endemic equilibria. A transcritical bifurcation is shown to exist among them, preventing bistability. The disease basic reproduction number is calculated. Simulations show that contact restrictive measures are able to delay the epidemic’s outbreak, if taken at a very early stage. However, if lifted too early, they could become ineffective. In particular, an intermittent lock-down policy could be implemented, with the advantage of spreading the epidemics over a longer timespan, thereby reducing the sudden burden on hospitals.
In this work, we introduce a minimal model for the current pandemic. It incorporates the basic compartments: exposed, and both symptomatic and asymptomatic infected. The dynamical system is formulated by means of fractional operators. The model equilibria are analyzed. The theoretical results indicate that their stability behavior is the same as for the corresponding system formulated via standard derivatives. This suggests that, at least in this case for the model presented here, the memory effects contained in the fractional operators apparently do not seem to play a relevant role. The numerical simulations instead reveal that the order of the fractional derivative has a definite influence on both the equilibrium population levels and the speed at which they are attained.
A B-cell chronic lymphocytic leukemia has been modeled via a highly nonlinear system of ordinary differential equations. We consider the rather important theoretical question of the equilibria existence. Under suitable assumptions all model populations are shown to coexist.
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