ObjectiveTo observe the effect and safety of cardiac rehabilitation (CR) exercise in ischemic cardiomyopathy and to compare the results between patients with preserved left ventricular ejection fraction (LVEF) and reduced LVEF.MethodsPatients with ischemic cardiomyopathy with LVEF <50% were included as subjects. The patients were classified into the preserved LVEF (pLVEF; LVEF 41%–49%) group and the reduced LVEF (rLVEF; LVEF ≤40%) group. Patients underwent hourly aerobic exercise training sessions with an intensity of 60%–85% of heart rate reserve, three times a week for 6 weeks. Graded exercise test and transthoracic echocardiogram were performed in all study patients before and after completion of the CR exercise program.ResultsAfter completion of the CR exercise program, both groups (pLVEF, n=30; rLVEF, n=18) showed significant increases in LVEF and VO2max. In the pLVEF group, LVEF and VO2max increased from 45.1%±4.8% to 52.5%±9.6% (p<0.001) and from 24.1±6.3 to 28.1±8.8 mL/kg/min (p=0.002), respectively. In the rLVEF group, LVEF and VO2max increased from 29.7%±7.7% to 37.6%±10.3% (p<0.001) and from 17.6±4.7 to 21.2±5.1 mL/kg/min (p<0.001), respectively. Both groups completed their exercise program safely.ConclusionIn both groups, patients with ischemic cardiomyopathy who completed a 6-week supervised CR exercise program demonstrated remarkable improvements in cardiopulmonary function. This result implies that neither of the two groups showed higher efficacy in comparison to each other, but we can conclude that CR exercise in the rLVEF group was as effective and safe as that in the pLVEF group.

The AS group had significantly increased TWD and decreased MST than the control group had (p¼0.001). The AS group had higher sway velocity in standing on firm base, lower speed in walk across and tandem walk tests (p<.030). AS patients with decreased MST had higher sway velocity on foam base (p¼.001 r¼-0.558). AS patients with decreased MST and increased TWD had larger step width in tandem walk (p¼.017 r¼-0.433; p¼.014 r¼0.443). As disease duration prolonged, MST decreased and step width increased in AS (p¼.021 r¼-0.420, p¼.0420 r¼0.433). VAS and BASDAI had no correlation with posture and balance. Conclusions: In AS patients, restricted spine flexibility impaired dynamic and static balance, prolonged disease duration impaired only the dynamic balance. We suggest assessment of posture and spine flexibilty should be inevitable part of AS follow-up to prevent balance disorders.Poster 142 Patient Characteristics Associated with Caregiver Burden of Patients with Malignant Brain Tumors.