Helicobacter pylori (H pylori) is a gram-negative, spiral-shaped bacterium that is known to have infected more than half of the world's population and is the only pathogenic bacteria currently known to survive in the human stomach. Helicobacter pylori is listed as grade 1 carcinogen in the list of carcinogens published by the World Health Organization. It changes the structure and function of the gastric mucosa following infection, eventually leading to a variety of gastric diseases. 1-3 Gastrin-17 (G-17) is an important gastrointestinal hormone which is mainly secreted by the gastrointestinal G cells. It stimulates the secretion of gastric acid and pepsinogen, promotes proliferation of the gastric mucosal cells, enhances the motility of the gastrointestinal tract, and promotes the secretion of pancreatic juice and bile.

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