No abstract

Construction monitoring of reinforced concrete arch bridge mainly include both the linear of structure and structural stress, comprehensive tracking control must be conducted to make smoothly construction of bridge and meet the design requirements. Taking 2# bridge in International Tourism Resort District of Changbai Mountain as the engineering background, according to features of sub-situ construction control of main arch, a reasonable program of construction control is adopted, to ensure that status of structural internal forces meet the design requirements or in a secure area during the construction process or after completion.

Purpose Immunogenic cell death (ICD) is a form of cell death that stimulates the immune system to produce an immune response by releasing tumor-associated antigens and tumor-specific antigens, and is considered to play an important role in tumor immunotherapy. Methods In the present study, we identified two ICD-related subtypes in osteosarcoma (OS) by consensus clustering. We also established and validated an ICD-related prognostic model. Result ICD-low subtype is associated with favorable clinical outcomes, abundant immune cell infiltration, and high activity of immune response signaling. The modle could not only be used to predict the overall survival of OS patients, but was also found to be closely related to the tumor immune microenvironment of OS patients. Conclusion We have established a new classification system for OS based on ICD-related genes, which can be used to predict the prognosis of OS patients and the selection of immunotherapy drugs.