Abstract. Purpose: to scientifically substantiate the role of para-vertebral impacts on blood circulation and bioelectrical activity of kick boxers' cortex. Material: in the research participated kick boxers (main group, n=62) and university students (control group, n=25) of 18-23 years' age. Assessment of para-vertebral impacts with device "Armos" and classic massage was fulfilled with the help of the following methodic: trans-cranial dopplerography of head main arteries and cortex EEG of the tested. Results: it was found that with the help of para-vertebral impacts by device "Armos" linear velocity of cerebral blood flow reduces to normal limits and in-and inter-hemispheres' interaction strength increases. Conclusions: para-vertebral impacts by device "Armos" activate integrative processes and inter-hemispheres' interactions of different cortex areas of kick boxers. It can witness about better formation of functional systems, ensuring sports efficiency.

Purpose : the comparative study of the immunity features of elite athletes of different sports. Material : study involved athletes of the highest mastery level of cyclic and acyclic sports (n = 147, age 18-23 years). Athletes were divided into groups by kinds of sport. Skiers (n = 54), swimmers (n = 23), wrestlers (n = 49), boxers (n = 21). Results : It was determined that athletes of acyclic sports (wrestlers and boxers) had a significant double increase in the level of secretory immunoglobulin IgA. In parallel, the level of immunoglobulins IgG is reduced. The highest indicators of lysosomal activity were recorded in skiers. Boxers, wrestlers, and swimmers had a decrease in the lysosomal activity level. The maximum phagocytic number is determined in wrestlers, and the minimum - in boxers. Conclusions : Comparative study of the immunity features of elite athletes in various sports suggests that there is a strain on the immune status. This condition is especially expressed in acyclic sports athletes (wrestling, boxing). This is due to the loads in the preparation process. The data received allow to confirm the significance of immune protection indicators in monitoring the athletes functional status.

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Aim. The article deals with establishing the peculiarities of ECG contour analysis in athletes with various SERPINE1 (PAI-1) genotypes depending on their gender. Materials and methods. We examined 200 athletes from national teams, including 107 boys aged 14.95 ± 1.57 and 93 girls aged 15.04 ± 1.67. ECG registration was performed in standard conditions using SENSITEG 1003 equipment. SERPINE1 PAI-1 gene mutation was assessed with the help of polymerase chain reaction using REALTIME DNA-technologies. We processed the results of the study using SPSS integrated statistical system. Results. We revealed that 44.1% and 55.1% of female and male athletes, respectively, possess SERPINE1 (PAI-1) gene heterozygous form. Dominant genotype was revealed in 23.7% and 33.6% of female and male athletes, respectively, while recessive genotype was found in 32.3% and 11.2% of female and male participants, respectively. Prolonged QRS, P intervals, associated with SERPINE1 (PAI-1) recessive genotype, are more typical for male participants (7-10%). Decreased HR and alpha angle values in persons with recessive genotype are 1.7 and 2.7 times more common for female athletes. Conclusion. We revealed electrocardiographic indicators, associated with SERPINE1 (PAI-1) gene mutation in young athletes. These indicators are significant for the assessment of cardiovascular disease risks. It was established that persons with SERPINE1 (PAI-1) 4G/4G genotype can practice professional sports only under the supervision of a cardiologist.