Monitoring system of wind turbine is the guarantee of normal operation of the wind turbine. It has significance on the study, promotion and application of wind turbines. The research status of wind turbine monitoring system was mainly elaborated. The structure of wind turbine monitoring system was analyzed. The monitoring systems based on VB, VC, configuration software and LabVIEW have been made a comparison. And several further research directions of the wind turbine monitoring system have been proposed.
The unique morphology and gene expression of podocytes are critical for kidney function, and their abnormalities lead to nephropathies such as diabetic nephropathy and membranous nephropathy. Podocytes cultured in vitro are valuable tools to dissect the molecular mechanism of podocyte injury relative to nephropathy, however, these models have never been comprehensively compared. Here, we comprehensively compared the morphology, cytoskeleton, cell adhesion, cell spreading, cell migration, and lipid metabolism under five commonly used in vitro models including lipopolysaccharide (LPS), puromycin aminonucleoside (PAN), doxorubicin (Dox), high glucose, and glucose deprivation. Our results indicate that all stimulations significantly downregulate the expression of synaptopodin both in human and mouse podocytes. All stimulations affect podocyte morphology but show different intensity and phenotypes. In general, the five stimulations reduce cell adhesion, cell spreading, and cell migration, but the effect in human and mouse podocytes is slightly different. Human podocytes show high expression of genes enriched in the pentose phosphate pathway. Dox and PAN treatment show a strong effect on gene expression in lipid metabolism, while the other three stimulations show minimal effect. The expression of phospholipase A2 receptor (PLA2R1) and type‐1 domain‐containing protein 7 A (THSD7A) show opposite trends in given cells. Stimulations can dramatically affect the expression of PLA2R1 and THSD7A. Inhibition of super‐enhancers reduces PLA2R1 and THSD7A expression, but ERK inhibition enhances their expression. Our results demonstrate distinctive responses in five commonly used in vitro podocyte injury models and the dynamic expression of PLA2R1 and THSD7A, which supply novel information to select suitable podocyte injury models.
<p>Physicochemical characteristics of the atmospheric boundary layer over North Plain China during the comprehensive observation experiment from 10 to 21 December 2018 were investigated in this paper. The observation data are obtained from the large tethered balloon, Doppler wind lidar, ground-level instruments. The maximum concentration of PM<sub>2.5</sub> exceeded 200 &#181;g m-3, and the ratio value of PM<sub>2.5</sub>/PM<sub>10</sub> was basically around 0.4 (maximum has reached approximately 0.8) during the whole observation period, indicating that explosive growth of fine ode dominant aerosols during the winter heating season. The peak solar irradiance was slightly larger on the clean day, compared with the value during the pollution process. The correlation coefficient between the concentration of PM<sub>2.5</sub> and CO was highest (0.725) among the gas pollutants, and the relationship between O<sub>3</sub> and PM<sub>2.5</sub> was basically negative correlated, not simple linear relationship. Three distinctly different vertical profile types of the PM<sub>2.5</sub> were categorized according to the vertical changes based on the total 33 vertical profiles obtained by the tethered balloon. Type 1 was mainly observed in the daytime, accounted for nearly 51.5%, the PM<sub>2.5</sub> concentration decreased nearly linearly as a function of height below approximate 600 m; Type 2 shows a sharp decreasing trend from the ground to about 200 m; Type 3 shows multi-layer structure of pollutants, some pollutants suspended aloft in upper air. The vertical profile of PM<sub>2.5</sub> was closely related to the atmospheric vertical structure such as the wind, temperature and turbulent kinetic energy, caused by the diurnal variation of the boundary layer. Small wind layer and the weak turbulence activities contributed to the accumulation of pollutants. Vertical patterns of the concentration of PM<sub>2.5</sub> were also greatly affected by the local ground emission sources and regional transport processes.</p>
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