Population genetics methods are used to study the relationship between living in the same environment and the formation of the large-intestine microflora in healthy persons. The variability of a microbiological phenotype is found to depend mainly on random factors and is virtually unrelated to the "familial" constituent.

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The age variability of the levels of antibodies against structurally different antigens is studied in female (NZBxNZW)F1 mice. It is established that the pubertal period is critical for the number of features studied and the degree of variability of autoantibody levels depends on the nature of the autoantigen.

No abstract