Background and Purpose-Diabetes mellitus (DM) is an independent risk factor for ischemic stroke. However, controversy exists with regard to the impact of DM on prognosis after ischemic stroke in the Chinese population. We investigated the associations between DM and death, dependency, and stroke recurrence in patients after ischemic stroke onset in a nationwide, prospective registry, the China National Stroke Registry. Methods-The China National Stroke Registry consecutively recruited patients hospitalized for acute ischemic stroke in 2007 to 2008 and who were prospectively followed up for clinical and functional outcomes (death, dependency, and stroke recurrence) at 3 and 6 months after disease onset. Multivariable logistic regression was performed to analyze the association between DM and stroke outcomes after adjusting for potential confounding including age, sex, National Institutes of Health Stroke Scale score, glucose level at admission, hypertension, coronary heart disease, smoking, urinary tract infection, and other factors. Results-DM was identified in 3483 (27.0%) of stroke patients. Compared with stroke patients without DM, patients with DM had a significantly higher incidence of death or dependency and of recurrent stroke at 3 and 6 months after stroke onset. DM was an independent risk factor for death or dependency (adjusted odds ratioϭ1.23; 95% confidence interval, 1.10 to 1.37) in patients with ischemic stroke at 6 months after onset. Conclusions-DM independently predicted poor outcomes in Chinese patients after acute ischemic stroke. (Stroke. 2011; 42:2758-2762.)

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The realization of large-scale H 2 production from electrocatalytic water splitting is severely impeded by the kinetically sluggish and economically less viable anodic oxygen evolution reaction.Here, an efficient strategy was established for the concurrent H 2 production and oxidative alcohols refining into value-added formate by utilizing self-supported Ni 2 PÀ CoP bifunctional electrocatalysts. Benefiting from high intrinsic activity, abundant active sites, and synergistic promoting effects of bimetallic phosphides, the constructed two-electrode electrolyzer required a cell voltage of around 1.3 V to achieve 10 mA cm À 2 , which is more than 200 mV lower than that of pure water splitting. Moreover, simultaneous productions of H 2 with nearunity conversion efficiency and formate at high faradaic efficiencies of 99.8 and 89.6 % oxidatively produced from methanol and glycerol, respectively, were achieved with excellent durability. This work presents a general and economic approach toward the fabrication of cost-effective electrocatalysts for energy-efficient and profitable large-scale renewable energy integration.

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