Leprosy or Hansen’s disease is a disease caused by obligate bacteria, Mycobacterium leprae. This disease is a chronic infectious disease with the first affinity in the peripheral nerves. The worst complication of this disease is disability and causes sufferers to be excluded from their social activities. There are several factors that play a role in the occurrence of leprosy defects, one of them is the type of leprosy. This research aims to determine the correlation between the type of leprosy and the grade of disability in leprosy patients in Samarinda. This research was an analytic observational study. Data collection was done by visiting all Community Health Center (Puskesmas) in Samarinda and the medical records of leprosy patients recorded from January 2014-February 2019. The sampling was using a purposive sampling technique. The result showed 106 patients who met the inclusion and exclusion criteria. Data analysis was using the Kolmogrov-Smirnov test which obtained p = 0.764, so it could be concluded that there was no correlation between the type of leprosy and the grade of disability in leprosy patients in Samarinda.

The Relation between Age, Pre-transfusion Hemoglobin Level and Duration of Sickness on Quality of Life in Children with Thalassemia in Samarinda. Thalassemia is a genetic disease caused bya disturbance in the process of forming the hemoglobin chain of red blood cells that decreased the production or formation of hemoglobin. Children with Thalassemia will have transfusions for their whole life to maintain blood hemoglobin levels. The older age of the child will also increase the frequent of blood transfusions to support the child’s growth.  Long and continuous transfusions also inadequate treatment will cause complications that affect the quality of life for people with Thalassemia. This study aims to analyze the relation between age, pre-transfusion hemoglobin level and duration of sickness on quality of life in children with Thalassemia in Samarinda. This research was an analytic observational study with a cross sectional design. The subjects were 32 children, aged 2-18 years, with major Thalassemia who werethe members of POPTI Samarinda. The data collected by medical records and the result from patient’s interview using PedsQl 4.0.  Statistical analysis use Pearson Test. The resultshows there isno relation between age and quality of life in children with Thalassemia (p = 0.136), there is relation between pre-transfusion hemoglobin level with the quality of life in children with Thalassemia (p = 0.040) and there is relation between duration of sickness and quality of life in children with Thalassemia (p = 0.036).  Based on the results of this study, it can be concluded that age has no relation to quality of life in children with  Thalassemia. Pre-transfusion hemoglobin level and duration of sickness have relation to quality of life in children with Thalassemia. Keywords: Thalassemia, quality of life, age, pre-transfusion hemoglobin level, duration of sickness.

Abstract Hepatocellular carcinoma (HCC) is a primary liver cancer that resulted from abnormal hepatocyte proliferation. HCC ranked fifth in the incidence of cancer cases and was the fourth leading cause of cancer death in the world in 2018. HCC patients have a poor prognosis and a low survival rate. This study aims to discover the incidence and characteristics of hepatocellular carcinoma in Abdul Wahab Sjahranie Regional Public Hospital Samarinda. The study design is a retrospective descriptive study. Data were obtained from patients' medical records data from February 2017 – February 2020. The result of this study were 206 HCC patients. From 206 patients, 82,5% were male and the oldest age group was 50-59 years old (33,5%); Hepatitis B (62,6%) was the most prevalent risk factor; 60,7% patients showed an increased level of AFP; 43,7% matched Child-Pugh B classification; 22,3% showed stage B BCLC; the most commonly used therapy was no-intervention therapy (93,2%). Survival rate was significantly affected by Child-Pugh classification (p=0,03) and BCLC stage (p=0,025). According to this study result, we can conclude that HCC incidence in the last 3 years is still high; HCC patients were predominantly male than female; the oldest age group was 50-59 years old; the most prevalent risk factor was Hepatitis B; HCC patients were more likely to develop increased AFP level; the most prevalent Child-Pugh classification was Child-Pugh B; the most prevalent stage was stage B and; 1-year survival rate was affected by Child-Pugh classification and BCLC stage. Keywords: Hepatocellular carcinoma, incidence, characteristics, the survival rate Abstrak Karsinoma hepatoseluler (KHS) merupakan kanker hati primer yang terjadi akibat tumbuhnya sel hepatosit secara abnormal. KHS menduduki peringkat kelima insidensi kasus kanker terbanyak dan urutan keempat penyebab kematian akibat kanker di dunia tahun 2018. Pasien KHS memiliki prognosis yang buruk dan survival rate yang rendah. Penelitian ini bertujuan untuk mengetahui insidensi dan karakteristik karsinoma hepatoseluler di RSUD Abdul Wahab Sjahranie Samarinda. Penelitian ini merupakan penelitian deskriptif retrospektif. Data yang digunakan dalam penelitian ini diperoleh dari data rekam medik pasien periode Februari 2017-Februari 2020. Hasil penelitian ini terdapat 206 pasien KHS. Dari 206 pasien 82,5% adalah laki-laki dengan kelompok usia tertinggi 50-59 tahun (33,5%), hepatitis B (62,6%) menjadi faktor risiko terbanyak, 60,7% pasien mengalami peningkatan level AFP, 43,7% menunjukkan klasifikasi Child-Pugh B, 22,3% menunjukkan stadium BCLC B, terapi paling banyak diberikan adalah terapi tanpa intervensi (93,2%). Survival rate secara signifikan dipengaruhi oleh klasifikasi Child-Pugh (p=0,017) dan stadium BCLC (p=0,037), tetapi survival rate tidak dipengaruhi oleh modalitas terapi (p=0,92). Berdasarkan penelitian ini dapat disimpulkan bahwa insidensi KHS pada 3 tahun terakhir masih tinggi, pasien KHS laki-laki lebih banyak daripada perempuan, kelompok usia tertinggi adalah kelompok usia 50-59 tahun, faktor risiko terbanyak adalah hepatitis B, pasien KHS lebih banyak mengalami peningkatan level AFP, klasifikasi Child-Pugh terbanyak adalah Child-Pugh B, stadium dengan jumlah terbanyak adalah stadium B, dan survival rate 1 tahun dipengaruhi oleh klasifikasi Child-Pugh dan stadium BCLC.   Kata kunci : Karsinoma hepatoseluler, insidensi, karakteristik, survival rate

ABSTRAKHipertensi adalah peningkatan tekanan darah yang disebabkan peningkatan curah jantung dan resistensi perifer pembuluh darah. Hipertensi dapat diobati dengan obat-obatan dan konsumsi buah serta sayur terutama buah yang mengandung kalium seperti pisang ambon. Penelitian ini bertujuan untuk mengetahui pengaruh konsumsi pisang ambon dalam membantu terapi penurunan tekanan darah pada penderita hipertensi di wilayah kerja Puskesmas Bontang Selatan. Metode yang digunakan adalah quasy experimental dengan desain non-equivalent control group. Sampel pada penelitian ini sebanyak 15 penderita hipertensi yang memenuhi kriteria inklusi. Analisis data menggunakan uji Paired T-Test, Wilcoxon Signed Ranks Test, Mann-Whitney dan Kruskal-Wallis. Hasil analisis univariat menunjukkan rata-rata tekanan darah kelompok kontrol sebelum perlakuan 152/92 mmHg dan setelah perlakuan 149,33/92 mmHg dibandingkan rata-rata tekanan darah kelompok perlakuan sebelum perlakuan 152/88,67 mmHg dan setelah perlakuan 137,33/84 mmHg. Hasil analisis bivariat menunjukkan tidak terdapat pengaruh variabel kelompok kontrol pada tekanan darah sistolik ataupun diastolik penderita hipertensi di Puskesmas Bontang Selatan serta terdapat pengaruh variabel kelompok perlakuan pada tekanan darah sistolik ataupun diastolik penderita hipertensi di Puskesmas Bontang Selatan. Kata Kunci: Hipertensi, Pisang ambon ABSTRACTHypertension is an increase in blood pressure caused by increased cardiac bulk and peripheral resistance of blood vessels. Hypertension can be treated with medications and consumption of fruits and vegetables, especially potassium-containing fruits such as ambon bananas. This study aims to find out the influence of banana consumption in helping blood pressure reduction therapy in hypertension patients in the working area of Puskesmas Bontang Selatan. The method used is quasy experimental with non-equivalent control group design. Samples in this study as many as 15 hypertension patients who met the inclusion criteria. Data analysis using Paired T-Test, Wilcoxon Signed Ranks Test, Mann-Whitney and Kruskal-Wallis. Univariate analysis results showed the average blood pressure of the control group before treatment was 152/92 mmHg and after treatment 149.33/92 mmHg compared to the average blood pressure of the treatment group before treatment of 152/88.67 mmHg and after treatment of 137.33/84 mmHg. The results of bivariate analysis showed that there was no influence of variable control group on systolic or diastolic blood pressure of hypertension patients in South Bontang Health Center and there was a variable influence of treatment group on systolic or diastolic blood pressure of hypertension patients at the South Bontang Health Center. Keywords: Hypertension, Ambon banana