The discharge characteristics of seawater batteries can be used to prolong the working hours of autonomous underwater observation vehicles. However, the output voltage level of the seawater battery is low, so it cannot directly be used to power supply underwater observation vehicles. In this paper, a boost converter is proposed based on the seawater batteries to power supply autonomous underwater observation vehicles. The proposed converter greatly increases the voltage level of the seawater battery and directly supplies the underwater observation vehicles. Compared with the traditional boost converter, the voltage gain of the proposed converter is more than ten times higher than it under the same duty ratio condition. Its structure is asymmetric interleaved parallel, which can enable power devices to obtain lower voltage stress and ensure that the input current ripple is low. The operating principle and homeostasis property of the proposed converter are analyzed in detail. Finally, a prototype is built. Through simulation and experiment, the correctness of the theoretical design is verified and experimental results are analyzed.