Jiao et al. show that the key player of antiviral immunity IRF3 binds to and promotes the transactivation of the YAP–TEAD4 complex to coregulate transcription of Hippo pathway target genes and that therapeutic targeting of IRF3 suppresses YAP-driven gastric cancer.

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With the development of Chang Qing Oilfield, the following technical problems are faced: the increasing proportion of the low-production and low-efficiency wells, the worse production of pertinence and effectiveness in conventional retreatments and a large amount of remaining oil between wells and layers. In this case, the technique of radial fracture network fracturing and deep plugging has been proposed. Meanwhile, the matching products which include variable viscosity diverting acid, micro expansion high strength plugging agent and temporary plugging agent (oil soluble, water soluble and anti-scale) have been developed as well. Nowadays, the retreatment technology has been successfully tested and popularized in Chang Qing oilfield. Compared with the conventional retreatments, these two technologies have remarkable effect on increasing production and prospective application.

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