Avoiding the plasma instability, especially the disruption instability, is an important problem for the stable operation of tokamak. Large-scale instabilities driven by free energy evolve nonlinearly and lead to the disruption. The microscale turbulence is highly sensitive to the change of free energy. The paper show the electron-scale turbulence evolution in the pre-precursor phase of TMs included disruption with the CO2 laser coherent scattering system in EAST. In the pre-precursor phase of disruption, it is observed that the characteristics of turbulence (e.g. intensity, spatial correlation) have obviously changed for more than 30 ms. In addition, before TM (n = 1) included major disruption, the spatial-correlation of turbulence in two regions (ρ = 0 − 0.4 and ρ = 0.4 − 0.8) increase obviously, while opposite turbulence spatial-correlation evolution was observed before TM (n = 1) included minor disruption. The warning time for disruption with microscale turbulence is competitive while 30 ms for ITER[1]. According to the experimental results in EAST, it may provide a new experimental evidence for the method improvement of predicting disruption.