Background Anterior chamber depth (ACD) is becoming a hot topic and plays an important role in correcting the refractive errors (REs) after cataract surgery. The aim of this study was to assess the ACD changes and their relationship with the REs after phacoemulsification and intraocular lens (IOL) implantation in patients with age-related cataracts. Methods One hundred forty-five eyes of 125 age-related cataract patients from the Department of Ophthalmology, Tangdu Hospital, China, were recruited. IOL Master was used for axial length (AL) and the IOL power calculation measurements, and the Pentacam HR device was used for the ACD and lens thickness (LT) measurements. Every patient underwent uncomplicated phacoemulsification by a single surgeon using a single technique. Postoperative refraction results were obtained at 1 month. The appropriate formula used for the IOL power calculation was chosen depending on the AL, specifically the Hoffer Q (AL < 22.0 mm), SRK/T (22.0 mm ≤ AL ≤ 30.0 mm), and Haigis (AL > 30.0 mm) formulas. Results The postoperative ACD was deepened and tended to stabilize gradually after 2 weeks. A concurrent hyperopic shift (0.57 ± 0.47 D) was observed when the change in the ACD was less than 1.65 mm, whereas a myopic shift (− 0.18 ± 0.62 D) occurred contrarily, and the difference between the two groups was statistically significant ( P < 0.0001). The change in ACD was significantly larger in the shallow anterior chamber (1.92 ± 0.40 mm) than in the deep chamber (1.33 ± 0.42 mm) ( P < 0.0001). Similarly, the change in ACD was larger in the short AL (2.12 ± 0.37 mm) than in the long AL (1.32 ± 0.49 mm). The postoperative ACD and refractive changes were correlated with the preoperative ACD and AL ( P < 0.0001), respectively. Two regression formulas were proposed: postoperative ACD = 3.524 + 0.294 × preoperative ACD and postoperative ACD = 3.361 + 0.228× (preoperative ACD + 1/2 LT). Conclusions The results of this study showed that the ACD deepened and was associated with a concurrent RE after cataract surgery. Postoperative changes in the ACD were related to the preoperative ACD and AL, which determined the refraction status and visual quality. The regression formula of the postoperative ACD could provide a theoretical basis for predicting refractive errors in the clinic.

Background: Reducing refractive error has always been a tricky problem. The aim of this study was to verify the correlation between binocular refractive error (RE) after sequential cataract surgery and explore an individualized calculation method of intraocular lens (IOL) for the second eye. Methods: This was a prospective study. One hundred eighty-eight affected eyes in 94 age-related cataract patients who underwent sequential cataract surgery in the Department of Ophthalmology, Tangdu Hospital, China, were recruited. Complete case data were included for a correlation analysis of binocular RE. Data obtained in patients with RE values greater than 0.50 diopters (D) in the first eye were extracted and the patients divided randomly into two groups: Group A and B. In the adjustment group, group A, we modified the IOL power for the second eyes as 50% of the RE of the first eye. In group B, the control group, there was no modification. The mean absolute refractive error (MARE) values of the second eyes were evaluated one month after surgery. Results: The correlation coefficient of the binocular RE after sequential cataract surgery was 0.760 (P < 0.001). After the IOL power of the second eyes was adjusted, the MARE of the second eyes was 0.57 ± 0.41 D, while the MARE of the first eyes was 1.18 ± 0.85 D, and the difference was statistically significant (P < 0.001). Conclusions: Binocular REs were positively correlated after sequential cataract surgery. The RE of the second eye can be reduced by adjusting the IOL power based on 50% of the postoperative RE of the first eye.

Background How to reduce the refractive error has always been a tricky problem. The aim of this study was to verify the correlation between binocular refractive errors (RE) after sequential cataract surgery and explore the individualized calculation method of intraocular lens (IOL) for the second eye. Methods This is a prospective study. One hundred eighty-eight affected eyes of 94 age-related cataract patients with sequential cataract surgery from the Department of Ophthalmology, Tangdu Hospital, china, were recruited. Complete case data of 94 patients were included for correlation analysis of binocular RE. Thereafter, data of patients with RE values greater than 0.50 diopter (D) in the first eyes were extracted and divided randomly into two groups- Group A and B. As the adjustment group, in group A we modified the IOL power for the second eyes according to 50% of the RE of the first eye, and group B was the control group without modify. The mean absolute refractive error (MARE) values of the second eyes were evaluated one month after surgery. Results The correlation coefficient of binocular RE after sequential cataract surgery was 0.760 ( P < 0.001). After the IOL power of the second eyes were adjusted, the MARE of the second eyes was 0.57±0.41 D while MARE of the first eyes was 1.18±0.85 D, and the difference was statistically significant ( P <0.001). Conclusions Binocular REs were correlated positively after sequential cataract surgery. The RE of the second eye can be reduced by adjusting the IOL power based on 50% of the postoperative RE of the first eye.

Background: How to reduce the refractive error has always been a tricky problem. The aim of this study was to verify the correlation between binocular refractive errors (RE) after sequential cataract surgery and explore the individualized calculation method of intraocular lens (IOL) for the second eye.Methods: This is a prospective study. One hundred eighty-eight affected eyes of 94 age-related cataract patients with sequential cataract surgery from the Department of Ophthalmology, Tangdu Hospital, china, were recruited. Complete case data of 94 patients were included for correlation analysis of binocular RE. Thereafter, data of patients with RE values greater than 0.50 diopter (D) in the first eyes were extracted and divided randomly into two groups- Group A and B. As the adjustment group, in group A we modified the IOL power for the second eyes according to 50% of the RE of the first eye, and group B was the control group without modify. The mean absolute refractive error (MARE) values of the second eyes were evaluated one month after surgery.Results: The correlation coefficient of binocular RE after sequential cataract surgery was 0.760 (P < 0.001). After the IOL power of the second eyes were adjusted, the MARE of the second eyes was 0.57±0.41 D while MARE of the first eyes was 1.18±0.85 D, and the difference was statistically significant (P<0.001).Conclusions: Binocular REs were correlated positively after sequential cataract surgery. The RE of the second eye can be reduced by adjusting the IOL power based on 50% of the postoperative RE of the first eye.