The combination of docetaxel plus nedaplatin was well tolerated and demonstrated potent activity in patients with metastatic NSCLC, particularly squamous cell carcinoma of the lung.

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Cavernous lymphangioma is a rare mediastinal benign tumor. A 43-year-old woman presented with cough and dyspnea for 1 month. Computed tomography of the chest showed a 3-cm well-circumscribed cystic mass in the posterior mediastinum. At thoracotomy, a cystic tumor in the mediastinum that was adherent to the descending aorta and esophagus was removed completely. The tumor, the cystic space of which was filled with lymph fluid, was diagnosed as cavernous lymphangioma based on pathological findings. Mediastinal lymphangiomas may insinuate into surrounding organs. As incomplete resection can result in recurrence, complete tumor removal should be performed based on accurate preoperative evaluation.

We report a case of multiple pulmonary hamartomas with a very unusual growth pattern. A 63-year-old woman underwent video-assisted thoracic surgery to investigate a round shadow seen on a routine chest radiograph. We found two tumors in the right S4, penetrating the visceral pleura and adhered to the right upper and lower lobes, respectively. Both tumors were removed and diagnosed histologically as pulmonary hamartoma. We hypothesized that these subpleural hamartomas might have grown invasively to penetrate the visceral pleura.

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