Implantable retinal prostheses are stimulation devices used to compensate for the light sensitivity loss of retinal cells. In this study, we propose and demonstrate a novel method to significantly reduce the setting time for the stimulation conditions of a retinal prosthesis chip capable of multi-electrode stimulation. The efficiency of the control method is increased while using only two wires, as in our previous work. The chip comprises an 8 bit ID and 7 electrodes, and the stimulation current value can be set from 50 to 1550 μA. The fabricated chip requires only 32 pulses to set the stimulation conditions, which is approximately 1/65 of that of our previous chip. Furthermore, it is equipped with a complementary metal–oxide–semiconductor rectifier to enable it to be driven by a rectangular AC power supply. The effectiveness of the chip is demonstrated by setting the stimulation conditions at approximately 18 μs per electrode at a clock frequency of 2.3 MHz.