Existing knowledge on remote working can be questioned in an extraordinary pandemic context. We conducted a mixed‐methods investigation to explore the challenges experienced by remote workers at this time, as well as what virtual work characteristics and individual differences affect these challenges. In Study 1, from semi‐structured interviews with Chinese employees working from home in the early days of the pandemic, we identified four key remote work challenges (work‐home interference, ineffective communication, procrastination, and loneliness), as well as four virtual work characteristics that affected the experience of these challenges (social support, job autonomy, monitoring, and workload) and one key individual difference factor (workers’ self‐discipline). In Study 2, using survey data from 522 employees working at home during the pandemic, we found that virtual work characteristics linked to worker's performance and well‐being via the experienced challenges. Specifically, social support was positively correlated with lower levels of all remote working challenges; job autonomy negatively related to loneliness; workload and monitoring both linked to higher work‐home interference; and workload additionally linked to lower procrastination. Self‐discipline was a significant moderator of several of these relationships. We discuss the implications of our research for the pandemic and beyond.

The novel coronavirus disease-2019 (COVID-19) has been spreading around the world rapidly and declared as a pandemic by WHO. Here, we compared the ABO blood group distribution in 2,173 patients with COVID-19 confirmed by SARS-CoV-2 test from three hospitals in Wuhan and Shenzhen, China with that in normal people from the corresponding regions. The results showed that blood group A was associated with a higher risk for acquiring COVID-19 compared with non-A blood groups, whereas blood group O was associated with a lower risk for the infection compared with non-O blood groups. This is the first observation of an association between the ABO blood type and COVID-19. It should be emphasized, however, that this is an early study with limitations. It would be premature to use this study to guide clinical practice at this time, but it should encourage further investigation of the relationship between the ABO blood group and the COVID-19 susceptibility.. All rights reserved. No reuse allowed without permission.

To explore any relationship between the ABO blood group and the COVID-19 susceptibility, we compared ABO blood group distributions in 2,173 COVID-19 patients with local control populations, and found that blood group A was associated with an increased risk of infection, whereas group O was associated with a decreased risk.

Highlights d Deletion of caspase-11 prevents disseminated intravascular coagulation (DIC) in sepsis d Deletion of GSDMD prevents caspase-11-and TF-mediated DIC in endotoxemia d GSDMD deficiency inhibits endotoxin-induced TF activation by reducing PS exposure d Activation of GSDMD by caspase-11 triggers Ca 2+dependent PS exposure through TMEM16F

No abstract