Asymmetric synthesis of the marine meroterpenoid dactyloquinone A was accomplished for the first time. The key advanced intermediate, a 6/6/6/6 tetracyclic core derivative was constructed by a bio-inspired Lewis acid-catalyzed...

A new approach was developed to construct a hexahydrobenzofurobenzopyran ring system by an oxa-[3+3], Diels–Alder reaction and oxidative aromatization. As a synthetic application, the bio-inspired formal synthesis of bisabosqual A was achieved.