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With the continuous development of industry, variable-section beams and high speed moving loads with large mass are widely used. Thus, it is of great significance to study the vibration response of variable-section beam with the consideration of inertia effect. Most past research focuses on the vibration response on uniform beams considering inertial effects, but there is little research on the vibration response of moving loads on variable section beam considering the inertia effect. In this paper, a variable section beam is simplified as a multi-stage ladder beam. Using the Euler-Bernoulli beam model, free-vibration characteristics and forced vibration characteristics of cantilever ladder beam are analysed. Following this step the vibration response considering the influence of the inertia effect is studied and compared with the situation that does not consider the influence of inertia effect. The results show that the mass, velocity, and acceleration of moving loads influence the effect of inertia on the response. Mass is the main factor affecting the results. The inertia effect caused by the acceleration and velocity can be ignored when the mass of moving load is small. The results have good engineering applicability.

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