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Background Sarcopenia has been associated with patients' poor quality of life, disability, and hospitalization. As of today, evidence that highlights the association between sarcopenia and Covid-19 outcomes remains unclear. This study sought to analyze whether patients with sarcopenia are at higher risk for developing poor Covid-19 outcomes. Methods Using specific keywords, we comprehensively go through the potential articles on medRxiv, Europe PMC, and PubMed sources until July 31 th , 2021. All published studies on sarcopenia and coronavirus disease 2019 were collected. We were using Review Manager 5.4 and Comprehensive Meta-Analysis 3 software to conduct statistical analysis. Results There were 9 studies with 492,245 Covid-19 patients included in the analysis. Evaluation of the data gathered yielded an association between sarcopenia and increased severity of Covid-19 (OR 1.99; 95%CI: 1.37 – 2.90, p =0.0003, I 2 = 79%, random-effect modelling); and mortality from Covid-19 (OR 1.96; 95%CI: 1.11 – 3.46, p =0.020, I 2 =49%, random-effect modelling). The increased risk of developing severe Covid-19 in a sarcopenic patient is also further influenced by cancer. Conclusions This study proposes that patients with sarcopenia are at risk of developing poor Covid-19 outcomes. Patients with sarcopenia need special attention and should be prioritized to receive the SARS-CoV-2 vaccine. Registration details PROSPERO (CRD42021270725)

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Background: Sacroiliac joint pain has been one of the most common causes of lower back pain, regardless of gender. Diminished pain after an anaesthetic block has been the only gold standard diagnostic procedure, making the diagnosis become challenging due to the needs of fluoroscopic procedure. Thus, a study to find predisposing factors of sacroiliac joint pain is pivotal for primary prevention and prognosis predictor. Objective: Our study aims to find predisposing factors of sacroiliac joint pain in Indonesian patients. Methods: We conducted a prospective study on patients with a chief complaint of lower back pain whose pain diminished after anaesthetic block. Results: We found 99 subjects, with a male to female ratio of 1:2.19, aged from 21 to 75 years old (mean: 42.88). In addition to multiparous pregnancy and obesity, office-based occupation and prolonged sitting duration are also becoming major predisposing factors of sacroiliac joint pain (50.5% and 51.51% respectively). We also found majority of the patients with a history of vertical trauma with the onset of pain 1 year post trauma. Conclusion: We found some factors that can be considered to trigger sacroiliac joint pain that are: female gender, advancing age, pregnancy history, long sitting duration and office worker occupation.