Herein, a synthetic polymer proteomimetic is described that reconstitutes the key structural elements and function of mussel adhesive protein. The proteomimetic was prepared via graft-through ring-opening metathesis polymerization of a norbornenyl-peptide monomer. The peptide was derived from the natural underwater glue produced by marine mussels that is composed of a highly repetitive 10 amino acid tandem repeat sequence. The hypothesis was that recapitulation of the repeating unit in this manner would provide a facile route to a nature-inspired adhesive. To this end, the material, in which the arrangement of peptide units was as side chains on a brush polymer rather than in a linear fashion as in the natural protein, was examined and compared to the native protein. Mechanical measurements of adhesion forces between solid surfaces revealed improved adhesion properties over the natural protein, making this strategy attractive for diverse applications. One such application is demonstrated, using the polymers as a surface adhesive for the immobilization of live cells.

High-throughput screening of mechanical properties can transform materials science research by both aiding in materials discovery and developing predictive models. However, only a few such assays have been reported, requiring custom or expensive equipment, while the mounting demand for enormous data sets of materials properties for predictive models is unfulfilled by the current characterization throughput. We address this problem by developing a high-throughput colorimetric adhesion screening method using a common laboratory centrifuge, multiwell plates, and microparticles. The technique uses centrifugation to apply a homogeneous mechanical detachment force across individual formulations in a multiwell plate. We also develop a high-throughput sample deposition method to prepare films with uniform thickness in each well, minimizing well-to-well variability. After establishing excellent agreement with the well-known probe tack adhesion test, we demonstrate the consistency of our method by performing the test on a multiwell plate with two different formulations in an easily discernible pattern. The throughput is limited only by the number of wells in the plates, easily reaching 10 3 samples/run. With its simplicity, low cost, and large dynamic range, this high-throughput method has the potential to change the landscape of adhesive material characterization.

Manganese slag contains a large number of easily migrated heavy metals and ammonia nitrogen and other pollutants, which have a negative impact on the ecological environment. To verify the feasibility of manganese slag as highway subgrade material, manganese slag samples were solidi ed by mixing y ash, cement and quicklime, and the solidi cation effect was compared. The permeability coe cient, cohesion and internal friction angle of manganese slag were measured by permeability test and triaxial test. On this basis, optimization of manganese slag road sections under different slope heights and different slope ratios in a total of 50 schemes was carried out. GeoStudio software is used to perform nite element simulation on the slope stability of manganese slag slopes under dead weight and rainfall.This study provides a reference for highway construction projects using manganese slag.

Machine learning approaches have introduced an urgent need for large datasets of materials properties. However, for mechanical properties, current high-throughput measurement methods typically require complex robotic instrumentation, with enormous capital...

During the running of nuclear power plant, corrosion products and impurities will be migrated from the secondary circuit to the steam generator. Some of them will stay inside the steam generator as sludge and they will gradually deposit on tube plate, the upper part of support plate, surface of tubes and the gap between the support plate and tubes. These sludge will be deposited on the surface of heat transfer tubes or on the tube plate, leading to the serious defects such as the corrosion inside steam generator and posing a major threat to the safe operation of nuclear power unit. In order to ensure the safe and stable running of nuclear power unit, it becomes particularly important to do evaluation on the deposition conditions of sludge in the certain area of evaporator. This paper adopts the non-destructive testing method based on eddy current and three-dimensional modeling & rendering engine of Unity3D to have a three-dimensional display on the deposition and distribution of sludge in multiple-pile evaporator. This clearly and effectively exhibits the sedimentation situation of sludge in evaporator, effectively improves the evaluation accuracy and provides an important basis for the subsequent sludge cleaning work.