Objective: To compare the outcomes of antibiotic therapy with and without bone debridement in diabetic foot osteomyelitis (DFO) patients. Methods: The surgical and orthopaedics Units of Islam Medical College conducted a prospective randomized comparison study on 100 diabetic individuals with DFO between January 1, 2020, and June-2021. Patients were separated into two groups: those who got just antibiotic therapy and those who had debridement and/or contemporaneous minor amputation. Three outcome indicators were evaluated between treatment groups: hospitalization time, antibiotic therapy time, and wound healing time. Results: Patient’s demographics e.g., age, BMI and gender were almost similar among groups. The hospital stay duration was 39.7±18.4 days in antibiotic versus 43.4±23.9 days in the combination group. Duration of antibiotics was 42.8±15.6 days in the antibiotic group versus 45.3±18.0 days in the combination group (p-value 0.45). Mean duration of wound healing was 230.8±120.8 days in antibiotic group versus 217.1±95.3 days in combination group (p-value 0.53). Conclusion: Our study has demonstrated comparable outcomes amongst individuals who got antibiotic treatment alone and those who had debridement and/or contemporaneous minor amputations. Keywords: diabetic foot osteomyelitis (DFO), Antibiotics, amputation.

Objective: To evaluate the outcomes of surgical excision vs aspiration combined with intralesional triamcinolone acetonide injection in the treatment of dorsal wrist ganglion (DWG). Methods: A total of 60 patients with diagnosis of DWG from January-2020 to December-2020 from Islam Teaching Hospital Sialkot were recruited for this comparative study. Two groups of patients were formed based on the kind of therapy they received. Aspiration and Triamcinolone acetate (triamcinolone acetate) injections were used in Group A. Treatment in Group B was comprised of aspiration followed by surgical excision. Follow-up was done at one, three, six, and twelve months after therapy ended. The absence of the cyst on the patient's last visit was considered proof of a successful therapy. Treatment was deemed ineffective if recurrence occurred. Results: Among 60 patients, 37 (61.7%) were female and 23 (38.3%) were males. The most common presenting symptom was swelling found in 60 (100%) patients, followed by pain/discomfort in 48 (80%) patients. Recurrence occurred in 5 (16.7%) patients in group B and in 4 (13.3%) patients in group A. The 1-year success rate was 86.7% in group A and 83.3% in group B (p-value 0.71). Conclusion: Aspiration followed by triamcinolone acetone injection is a good alternative to surgical excision in DWG patients. Keywords: Aspiration, Surgical excision, Dorsal wrist ganglion.