Original scientific paperIn this study, the effects of bone ash and maleic anhydride grafted polypropylene (MAPP) additives used in polypropylene (PP)/polyamide 6 (PA6) blends on the mechanical and tribological properties of the composites were investigated. Bone powder is a waste material especially in food industry. The use of bone powder in polymer matrix composites is important because of the reduction of petroleumbased content in the composites and its biodegradable characteristic. The composites were produced using a twin-screw extruder by melt blending method and then molded to sample sizes to be used in mechanical and tribological tests by injection molding. Tensile test, threepoint bending test, Shore D hardness test and ball-on-disc sliding wear tests were carried out on the composites and the results were compared with respect to the composite composition. When the results were examined, it was found that the bone ash additive was more effective on the hardness and the compatibilizer additive was more effective on the tensile and bending strength. The highest hardness values were achieved with 20% and 30% bone ash additives. It has been found that bone ash is also very effective in reducing the friction coefficients, especially when used with compatibilizer it reduces the wear rates significantly (up to 98%). In summary, PP/PA6 matrix composites obtained with the synergistic effect of bone ash and MAPP are promising for applications requiring mechanical and wear resistance.